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Merck
CN

L6543

Lacto-N-neo-tetraose

synthetic, ≥85% (HPLC)

别名:

β-D-Gal-(1→4)-β-D-GlcNAc-(1→3)-β-D-Gal-(1→4)-D-Glc, LNnT

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关于此项目

经验公式（希尔记法）:
C26H45NO21
化学文摘社编号:
13007-32-4
分子量:
707.63
NACRES:
NA.25
PubChem Substance ID:
24896438
UNSPSC Code:
12352201
MDL number:
MFCD00467190

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InChI key

RBMYDHMFFAVMMM-UHFFFAOYSA-N

SMILES string

CC(=O)NC1C(O)C(OC2OC(CO)C(O)C(O)C2O)C(CO)OC1OC3C(O)C(CO)OC(OC(C(O)CO)C(O)C(O)C=O)C3O

InChI

1S/C26H45NO21/c1-7(33)27-13-17(39)22(47-25-19(41)18(40)15(37)10(4-30)43-25)12(6-32)45-24(13)48-23-16(38)11(5-31)44-26(20(23)42)46-21(9(35)3-29)14(36)8(34)2-28/h2,8-26,29-32,34-42H,3-6H2,1H3,(H,27,33)

biological source

synthetic

assay

≥85% (HPLC)

form

powder

storage temp.

2-8°C

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存储类别

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
BCBM9050V
SLBH0057V
SLBF3582V
SLBF3582
SLBB8736

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David A Sela et al.
The Journal of biological chemistry, 286(14), 11909-11918 (2011-02-04)
Lactating mothers secrete milk sialyloligosaccharides (MSOs) that function as anti-adhesives once provided to the neonate. Particular infant-associated commensals, such as Bifidobacterium longum subsp. infantis, consume neutral milk oligosaccharides, although their ability to utilize acidic oligosaccharides has not been assessed. Temporal
Lars Bode et al.
The American journal of clinical nutrition, 96(4), 831-839 (2012-08-17)
The inefficiency of HIV breast-milk transmission may be caused by the presence of immunologically active factors, including human milk oligosaccharides (HMOs). We investigated whether HMO concentrations are associated with a reduced risk of postnatal HIV transmission. A nested case-control study
Xiaomin Dong et al.
Biotechnology for biofuels, 12, 212-212 (2019-09-14)
Lacto-N-neotetraose (LNnT) is one of the important ingredients of human milk oligosaccharides, which can enhance immunity, regulate intestinal bacteria and promote cell maturation. In this study, the synthetic pathway of LNnT was constructed by co-expressing the lactose permease (LacY) β-1,3-N-acetylglucosaminyltransferase
Stephen A Fleming et al.
Frontiers in neuroscience, 14, 770-770 (2020-09-10)
Human milk contains a unique profile of oligosaccharides (OS) and preliminary evidence suggests they impact brain development. The objective of this study was to assess the impact of bovine and/or human milk oligosaccharides (HMO) (2'-fucosyllactose and Lacto-N-neotetraose) on cognition, brain
Alexandra S Tauzin et al.
Microbiome, 8(1), 141-141 (2020-10-03)
Despite the importance of the mucosal interface between microbiota and the host in gut homeostasis, little is known about the mechanisms of bacterial gut colonization, involving foraging for glycans produced by epithelial cells. The slow pace of progress toward understanding
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