biological source
Escherichia coli (F583 Rd mutant)
Quality Level
form
lyophilized powder
impurities
<0.2% Ketodeoxyoctonate (KDO)
shipped in
ambient
storage temp.
2-8°C
Biochem/physiol Actions
脂质A具有免疫刺激佐剂活性,包括巨噬细胞、T细胞和B细胞活化。研究表明脂质A对于Th2有比Th1更大的刺激。
脂质A分子组成了由革兰氏阴性菌所产生的内毒素的脂膜锚定核心成分。脂质A分子可诱导免疫反应。结构上,脂质A分子由两个物种依赖性、脂肪酰基链数、同一性和磷酸化程度均不同的葡糖胺单元所组成。
来自大肠杆菌F583的单磷酰基脂质A可用于对不同LPA分子和类似物内特定结构的抗原性进行比较性评估。
来自大肠杆菌F583的单磷酰基脂质A可用于对不同LPA分子和类似物内特定结构的抗原性进行比较性评估。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
相关内容
Product Information Sheet
Vincent J Venditto et al.
Clinical and vaccine immunology : CVI, 20(1), 39-45 (2012-11-02)
The inability to generate broadly neutralizing antibody (bnAb) responses to the membrane proximal external region (MPER) of HIV-1 gp41 using current vaccine strategies has hampered efforts to prevent the spread of HIV. To address this challenge, we investigated a novel
Vincent J Venditto et al.
Clinical and vaccine immunology : CVI, 21(8), 1086-1093 (2014-05-30)
Broadly neutralizing monoclonal antibodies (bNAbs) 2F5 and 4E10 bind to the membrane proximal external region (MPER) of gp41 and also cross-react with phospholipids. In this study, we investigated if chemical modifications on the MPER adjacent to 2F5 and 4E10 epitopes
Mark B Stoddard et al.
Clinical and vaccine immunology : CVI, 17(1), 98-107 (2009-11-20)
Bacterial endotoxin interacts with the human immune system via complex immunological pathways. The evaluation of endotoxicity is important in the development of safe vaccines and immunomodulatory therapeutics. The Limulus amebocyte lysate (LAL) assay is generally accepted by the FDA for
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| L6638-1MG | 04061826677438 |
| L6638-5MG | 04061833275177 |