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L6668

Lercanidipine 盐酸盐

Name: Lercanidipine 盐酸盐
Brand: SIGMA

≥98% (HPLC), powder, dihydropyridine calcium-channel blocker

别名:

1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-2-[(3,3-diphenylpropyl)methylamino]-1,1-dimethylethyl methyl ester 3,5-pyridinedicarboxylic acid hydrochloride

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关于此项目

经验公式（希尔记法）:

C₃₆H₄₁N₃O₆ · HCl

化学文摘社编号:

132866-11-6

分子量:

648.19

UNSPSC Code:

12352200

PubChem Substance ID:

24724527

NACRES:

NA.77

MDL number:

MFCD07773089

Assay:

≥98% (HPLC)

Form:

powder

Storage condition:

desiccated, protect from light

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属性

产品名称

Lercanidipine 盐酸盐, ≥98% (HPLC)

assay

≥98% (HPLC)

form

powder

storage condition

desiccated, protect from light

color

yellow

originator

Forest Labs

storage temp.

2-8°C

SMILES string

O=C(OC)C1=C(C)NC(C)=C(C(OC(C)(C)CN(C)CCC(C2=CC=CC=C2)C3=CC=CC=C3)=O)C1C4=CC([N+]([O-])=O)=CC=C4.Cl

InChI

1S/C36H41N3O6.ClH/c1-24-31(34(40)44-6)33(28-18-13-19-29(22-28)39(42)43)32(25(2)37-24)35(41)45-36(3,4)23-38(5)21-20-30(26-14-9-7-10-15-26)27-16-11-8-12-17-27;/h7-19,22,30,33,37H,20-21,23H2,1-6H3;1H

InChI key

WMFYOYKPJLRMJI-UHFFFAOYSA-N

说明

Biochem/physiol Actions

Lercanidipine hydrochloride is a L-type (Ca_v1.2b) vascular channel antagonist; L-type (Ca_v1.2a) cardiac channel agonist voltage-dependent and highly lipophylic compound, which exhibits a slower onset and longer duration of action than other calcium channel antagonists; an antihypertensive agent in patients with mild-to-moderate hypertension; more vasoselective than lacidipine and amlodipine.

Lercanidipine hydrochloride is a L-type (Ca_v1.2b) vascular channel antagonist; L-type (Ca_v1.2a) cardiac channel agonist.

Features and Benefits

This compound was developed by Forest Labs. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

pictograms

GHS06

signalword

Danger

hcodes

H301

pcodes

P264 - P270 - P301 + P310 - P405 - P501

Hazard Classifications

Acute Tox. 3 Oral

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c