L6670
LY266097
≥98% (HPLC), powder
别名:
1-[(2-Chloro-3,4-dimethoxyphenyl)methyl]-2,3,4,9-tetrahydro-6-methyl-1H-pyrido[3,4-b]indole hydrochloride, LY 266097
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关于此项目
经验公式（希尔记法）:
C21H23ClN2O2 · HCl
化学文摘社编号:
分子量:
407.33
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
InChI key
KPXKZZURYAXZQE-UHFFFAOYSA-N
SMILES string
Cl.COc1ccc(CC2NCCc3c2[nH]c4ccc(C)cc34)c(Cl)c1OC
InChI
1S/C21H23ClN2O2.ClH/c1-12-4-6-16-15(10-12)14-8-9-23-17(20(14)24-16)11-13-5-7-18(25-2)21(26-3)19(13)22;/h4-7,10,17,23-24H,8-9,11H2,1-3H3;1H
assay
≥98% (HPLC)
form
powder
storage condition
desiccated
color
white to tan
solubility
DMSO: ≥20 mg/mL
originator
Eli Lilly
storage temp.
2-8°C
Quality Level
Biochem/physiol Actions
LY266097 is a selective 5HT-2B antagonist with a pKI of 9.7 for the human cloned 5-HT2B receptor and a 100-fold greater selectivity for 5-HT2B than the human 5-HT2C and 5-HT2A.
LY266097 is a selective 5HT-2B antagonist.
Features and Benefits
This compound was developed by Eli Lilly. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Céline Devroye et al.
Neuropharmacology, 109, 59-68 (2016-06-05)
Recent studies suggest that the central serotonin2B receptor (5-HT2BR) could be an interesting pharmacological target for treating neuropsychiatric disorders related to dopamine (DA) dysfunction, such as schizophrenia. Thus, the present study was aimed at characterizing the role of 5-HT2BRs in
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