L7901
Monoclonal Anti-LEF-1 (HMG DNA Binding Domain) antibody produced in mouse
~1 mg/mL, clone REMB6, purified immunoglobulin
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关于此项目
Conjugate:
unconjugated
Clone:
REMB6, monoclonal
Application:
WB
Citations:
2
biological source
mouse
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
REMB6, monoclonal
mol wt
antigen 55-57 kDa
species reactivity
human
concentration
~1 mg/mL
technique(s)
western blot: 1-5 μg/mL using whole extracts of human Jurkat cells or transiently expressed human LEF-1 in whole cell lysates from Cos-1 cells
isotype
IgG1
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... LEF1(51176)
Immunogen
full length recombinant LEF-1.
Application
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)
Western Blotting (1 paper)
Physical form
Solution in 0.01 M phosphate buffered saline, pH 7.5, containing 0.08% sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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存储类别
10 - Combustible liquids
法规信息
常规特殊物品
低风险生物材料
此项目有
Upregulation of endogenous ICAM-1 reduces ovarian cancer cell growth in the absence of immune cells.
Marloes L de Groote et al.
International journal of cancer, 134(2), 280-290 (2013-07-09)
Ovarian cancer is a difficult-to-treat cancer with a 5-year survival rate of only ∼45%, due to late diagnosis and therapy resistance. In need of new therapeutic approaches, induction of intercellular adhesion molecule (ICAM)-1 expression might be of interest, since the
Elisabetta Lambertini et al.
BMC molecular biology, 11, 13-13 (2010-02-05)
Lymphoid Enhancer Factor-1 (Lef-1) is a member of a transcription factor family that acts as downstream mediator of the Wnt/beta-catenin signalling pathway which plays a critical role in osteoblast proliferation and differentiation. In a search for Lef-1 responsive genes in
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