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Merck
CN

L7920

β-Lactamase Blend

recombinant, expressed in E. coli

别名:

Carbapenemase, Cephalosprinase

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关于此项目

NACRES:
NA.54
UNSPSC Code:
12352204
Recombinant:
expressed in E. coli
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recombinant

expressed in E. coli

Quality Level

sterility

γ-irradiated

form

lyophilized powder

storage temp.

2-8°C

General description

No detectable growth in tryptone soy broth at 30-35 °C for 14 days

Biochem/physiol Actions

β-Lactamases exhibit high carbapenemase activity. β-lactamases can destroy the β-lactam ring. True carbapenemases has the ability to hydrolyse several β-lactam ring containing carbapenems like meropenem, doripenem, imipenem and ertapenem.

Physical form

Lyophilized powder containing sodium chloride, potassium phosphate, dipotassium phosphate and sorbitol.

Other Notes

600-1500 IU beta-lactamase I per vial
60-150 IU beta-lactamase II per vial
One unit will hydrolyze 1.0 μmole substrate per min (βI: benzylpenicillin; βII: cephalosporin C) in phosphate buffer, pH 7.0 at 25°C.

pictograms

Health hazard

signalword

Danger

hcodes

Hazard Classifications

Resp. Sens. 1 - Skin Sens. 1

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

常规特殊物品

此项目有


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Lisa M Miller et al.
ACS applied materials & interfaces, 11(36), 32599-32604 (2019-08-27)
Antimicrobial resistance (AMR) has been identified as a major threat to public health worldwide. To ensure appropriate use of existing antibiotics, rapid and reliable tests of AMR are necessary. One of the most common and clinically important forms of bacterial
Mechanisms and Detection of Antimicrobial Resistance
Principles and Practice of Pediatric Infectious Diseases (Fourth Edition), 1467-1478 (2017)
Identification and screening of carbapenemase-producing Enterobacteriaceae
Nordmann P, et al.
Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases, 18(5), 432-438 (2012)
Matthew D Simmons et al.
Antibiotics (Basel, Switzerland), 9(10) (2020-10-03)
The misuse of antibiotics in health care has led to increasing levels of drug resistant infections (DRI's) occurring in the general population. Most technologies developed for the detection of DRI's typically focus on phenotyping or genotyping bacterial resistance rather than
Joseph E Rubin et al.
Veterinary microbiology, 170(1-2), 10-18 (2014-03-01)
Organisms in the family Enterobactericeae including, Escherichia coli, commonly cause community and hospital-associated infections in both humans and companion animals. The increasing prevalence of infections with organisms producing broad spectrum β-lactamses such as the ESBLs (particularly the CTX-M type), AmpC

全球贸易项目编号

货号GTIN
L7920-1VL04061838114013

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