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Merck
CN

L7920

Sigma-Aldrich

β-Lactamase Blend

recombinant, expressed in E. coli

别名:

Carbapenemase, Cephalosprinase

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关于此项目

UNSPSC代码:
12352204
NACRES:
NA.54
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重组

expressed in E. coli

质量水平

无菌性

γ-irradiated

表单

lyophilized powder

储存温度

2-8°C

一般描述

No detectable growth in tryptone soy broth at 30-35 °C for 14 days

生化/生理作用

β-Lactamases exhibit high carbapenemase activity. β-lactamases can destroy the β-lactam ring. True carbapenemases has the ability to hydrolyse several β-lactam ring containing carbapenems like meropenem, doripenem, imipenem and ertapenem.

外形

Lyophilized powder containing sodium chloride, potassium phosphate, dipotassium phosphate and sorbitol.

其他说明

600-1500 IU beta-lactamase I per vial
60-150 IU beta-lactamase II per vial
One unit will hydrolyze 1.0 μmole substrate per min (βI: benzylpenicillin; βII: cephalosporin C) in phosphate buffer, pH 7.0 at 25°C.

象形图

Health hazard

警示用语:

Danger

危险声明

危险分类

Resp. Sens. 1 - Skin Sens. 1

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

常规特殊物品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Mechanisms and Detection of Antimicrobial Resistance
Principles and Practice of Pediatric Infectious Diseases (Fourth Edition), 1467-1478 (2017)
Lisa M Miller et al.
ACS applied materials & interfaces, 11(36), 32599-32604 (2019-08-27)
Antimicrobial resistance (AMR) has been identified as a major threat to public health worldwide. To ensure appropriate use of existing antibiotics, rapid and reliable tests of AMR are necessary. One of the most common and clinically important forms of bacterial
Matthew D Simmons et al.
Antibiotics (Basel, Switzerland), 9(10) (2020-10-03)
The misuse of antibiotics in health care has led to increasing levels of drug resistant infections (DRI's) occurring in the general population. Most technologies developed for the detection of DRI's typically focus on phenotyping or genotyping bacterial resistance rather than
Identification and screening of carbapenemase-producing Enterobacteriaceae
Nordmann P, et al.
Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases, 18(5), 432-438 (2012)
Jun Hirose et al.
The Journal of experimental medicine, 211(1), 153-163 (2013-12-25)
Signal transducer and activator of transcription 5 (Stat5) is essential for cytokine-regulated processes such as proliferation, differentiation, and survival in hematopoietic cells. To investigate the role of Stat5 in osteoclasts, we generated mice with an osteoclast-specific conditional deletion of Stat5

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