生物来源
plant oil (safflower)
质量水平
方案
≥97% (GC)
表单
powder
技术
activity assay: suitable
颜色
white
mp
230 °C (446 °F)
溶解性
methanol: 50 mg/mL, clear, yellow
应用
general analytical
life science and biopharma
官能团
carboxylic acid
脂质类型
omega FAs
运输
ambient
储存温度
−20°C
SMILES字符串
[Na+].CCCCC\C=C/C\C=C/CCCCCCCC([O-])=O
InChI
1S/C18H32O2.Na/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20;/h6-7,9-10H,2-5,8,11-17H2,1H3,(H,19,20);/q;+1/p-1/b7-6-,10-9-;
InChI key
WYPBVHPKMJYUEO-NBTZWHCOSA-M
一般描述
亚油酸是一种ω-6多不饱和必需脂肪酸(PUFA)，它是花生四烯酸(AA)的前体，也是合成前列腺素和其它类二十烷酸的必要物质。作为一种必需脂肪酸，亚油酸必须通过膳食获取，因为人体不能生成它。亚油酸缺乏与伤口愈合不良、生长迟缓和皮炎等健康问题有关。花生四烯酸15脂氧合酶（15-LO）可以代谢植物和动物体内的亚油酸，从而形成9-和13-羟基十八碳二烯酸（HODE）。这种多功能分子的应用领域包括生物化学、代谢组学和脂质组学研究，它便于研究人员研究各种代谢途径，并提供了有关活生物体内脂质功能的信息。
应用
亚油酸钠盐已用于：
- β-胡萝卜素亚油酸含量测定
- 用作基础培养基成分，处理外周血单核细胞（PBMC）
- 杜氏改良 Eagle培养基（DMEM）/F-12 HEPES（4-（2-羟乙基）哌嗪-1-乙磺酸），孵育人滋养层来源的绒毛膜癌细胞（BeWo），并研究其对粘附连接（AJ）标记水平、细胞层通透性和细胞内脂质积聚的影响
生化/生理作用
作为酰基糖基神经酰胺组分，亚油酸在维持皮肤的透水屏障方面发挥着生理作用。亚油酸缺乏可能导致婴儿生长发育不良、鳞状皮炎和免疫反应受损。这一物质用于化妆品和个人护理产品。亚油酸主要用作皮肤、指甲和头发的润肤剂或保湿剂。
特点和优势
- 适用于多种研究应用的优质分子
- 常用于代谢组学和生物化学研究
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Hila Seti et al.
Archives of physiology and biochemistry, 115(3), 127-136 (2009-06-02)
The insulin-like growth factor (IGF) system plays a critical role in normal growth and development as well as in malignant states. Most of the biological activities of the IGFs are mediated by the IGF-IR, which is over-expressed in most tumours
E P Kilsdonk et al.
Journal of lipid research, 33(9), 1373-1382 (1992-09-01)
Human endothelial cells (EA.hy 926 line) were loaded with cationized low density lipoprotein (LDL) and subsequently incubated with fatty acid/bovine serum albumin complexes. The fatty acids were palmitic, oleic, linoleic, arachidonic, and eicosapentaenoic acids. The preincubations resulted in extensively modified
Moran Cohen-Berkman et al.
eLife, 9 (2020-03-28)
How lifespan and the rate of aging are set is a key problem in biology. Small RNAs are conserved molecules that impact diverse biological processes through the control of gene expression. However, in contrast to miRNAs, the role of endo-siRNAs
Miriam E van Gent et al.
Antibiotics (Basel, Switzerland), 11(5) (2022-05-29)
Recently, using a deep learning approach, the novel antibiotic halicin was discovered. We compared the antibacterial activities of two novel bactericidal antimicrobial agents, i.e., the synthetic antibacterial and antibiofilm peptide (SAAP)-148 with this antibiotic halicin. Results revealed that SAAP-148 was
Alketa Tarushi et al.
Journal of inorganic biochemistry, 170, 85-97 (2017-02-24)
From the reaction of ZnCl
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持