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Merck
CN

L8402

溶菌酶 来源于人类中性粒细胞

≥95% (SDS-PAGE), lyophilized powder, ≥100,000 units/mg protein (E1%/280)

别名:

粘肽N-乙酰胞壁质水解酶, 胞壁质酶

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关于此项目

化学文摘社编号:
9001-63-2
NACRES:
NA.54
UNSPSC Code:
12352204
MDL number:
MFCD00131557
EC 号:
3.2.1.17 (BRENDA, IUBMB)
Specific activity:
≥100,000 units/mg protein (E1%/280)
Assay:
≥95% (SDS-PAGE)
Biological source:
human neutrophils
Recombinant:
expressed in E. coli

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SMILES string

N1([C@@H](CCC1)C(=O)N[C@@H](CCC(=O)N)C(=O)NCC(=O)N[C@@H]([C@H](CC)C)C(=O)N[C@@H](CCCN\C(=N\[H])\N)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc4c5c([nH]c4)cccc5)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc2c3c([nH]c2)cccc3)C(=O)N[C@@H](CCCN\C(=N\[H])\N)C(=O)N[C@@H]

InChI

1S/C99H159N37O23/c1-11-50(8)77(132-72(139)46-120-81(145)63(32-33-70(101)137)124-88(152)69-31-21-39-136(69)93(157)68(43-73(140)141)131-84(148)62(29-19-37-116-98(109)110)125-90(154)75(48(4)5)135-91(155)76(49(6)7)133-80(144)57(100)24-16-34-113-95(103)104)92(156)126-60(27-17-35-114-96(105)106)82(146)121-51(9)78(142)129-66(41-54-45-119-59-26-15-13-23-56(54)59)87(151)134-74(47(2)3)89(153)122-52(10)79(143)128-65(40-53-44-118-58-25-14-12-22-55(53)58)85(149)123-61(28-18-36-115-97(107)108)83(147)130-67(42-71(102)138)86(150)127-64(94(158)159)30-20-38-117-99(111)112/h12-15,22-23,25-26,44-45,47-52,57,60-69,74-77,118-119H,11,16-21,24,27-43,46,100H2,1-10H3,(H2,101,137)(H2,102,138)(H,120,145)(H,121,146)(H,122,153)(H,123,149)(H,124,152)(H,125,154)(H,126,156)(H,127,150)(H,128,143)(H,129,142)(H,130,147)(H,131,148)(H,132,139)(H,133,144)(H,134,151)(H,135,155)(H,140,141)(H,158,159)(H4,103,104,113)(H4,105,106,114)(H4,107,108,115)(H4,109,110,116)(H4,111,112,117)/t50-,51-,52-,57-,60-,61-,62-,63-,64-,65-,66-,67-,68-,69-,74-,75-,76-,77-/m0/s1

InChI key

ZJCXKXFAOCLSRV-RYLVIXIQSA-N

biological source

human neutrophils

recombinant

expressed in E. coli

assay

≥95% (SDS-PAGE)

form

lyophilized powder

specific activity

≥100,000 units/mg protein (E1%/280)

technique(s)

cell based assay: suitable

suitability

suitable for cell lysis

UniProt accession no.

P61626

application(s)

cell analysis

storage temp.

−20°C

Quality Level

200

Gene Information

human ... LYZ(4069)

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相关类别

General description

溶菌酶大量存在于动植物界。它是一种天然食品防腐剂，也存在于特定的细菌细胞壁中。溶菌酶通常存在于泪液、乳汁、尿液和唾液中。

Application

人中性粒细胞溶菌酶已被用于棋盘法，以建立拟肽 1 与免疫效应分子之间的协同抗大肠杆菌。

Biochem/physiol Actions

溶菌酶参与防御机制。具有通过在底物中产生空间应力刺激催化的能力。

Physical form

从含 100 mM NaCl 的 50 mM 乙酸钠 (pH 6.0) 冻干

Other Notes

更多关于复杂碳水化合物分析酶的信息请见 www.sigma-aldrich.com/enzymeexplorer
酶用缓冲液悬浮后，在pH 6.2、25 °C下，1单位每分钟可释放0.6 μg溶壁微球菌（浊度法检测，600nm）。

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

常规特殊物品
此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000387195
0000372170
0000372170
0000387195
0000294498

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实验方案

Enzymatic Assay of Lysozyme (EC 3.2.1.17)

This enzymatic rate determination may be used for Lysozyme products. It is not to be used to assay recombinant or insoluble Lysozyme on agarose.

溶菌酶的酶学测定（EC 3.2.1.17）

该酶速率测定可用于溶菌酶产物。它不适用于在测定在琼脂糖上的重组型或不溶性溶菌酶。

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