产品名称
DL -羊毛硫氨酸, ≥98% (TLC)
Quality Level
assay
≥98% (TLC)
form
powder
color
white
solubility
1 M HCl: soluble
application(s)
detection
SMILES string
S(CC(N)C(=O)O)CC(N)C(=O)O
InChI
1S/C6H12N2O4S/c7-3(5(9)10)1-13-2-4(8)6(11)12/h3-4H,1-2,7-8H2,(H,9,10)(H,11,12)
InChI key
DWPCPZJAHOETAG-UHFFFAOYSA-N
Application
- Synthesis of the lantibiotic lactocin S using peptide cyclizations on solid phase.：采用创新方法合成肽基抗生素，如乳酸链球菌素S(lactocin S)，过程中利用dl-羊毛硫氨酸形成重要的硫醚交联，提高多肽的活性和稳定性(Ross et al., 2010)。
- Cystathionine gamma-lyase of Streptomyces phaeochromogenes.：分离和鉴定一种处理胱硫醚的酶，其中dl-羊毛硫氨酸被作为结构类似物，揭示其细菌生理学作用和生物技术应用潜力(Nagasawa et al., 1984)。
- The availability of dl-lanthionine for the promotion of growth in young rats when added to a cystine- and methionine-deficient diet.：该古早研究探讨dl-羊毛硫氨酸的营养价值，评估其取代生长饮食必需氨基酸的能力，有助了解其在营养补充剂中的潜在用途(Jones et al., 1948)。
Biochem/physiol Actions
羊毛硫氨酸是一种非典型氨基酸，是胱氨酸的单硫化物类似物。羊毛硫氨酸是一组肽类抗生素的成分，称为羊毛硫抗生素，其中包括乳链菌肽和枯草菌素。
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Jun-ichi Nagao et al.
Current pharmaceutical biotechnology, 12(8), 1221-1230 (2011-04-08)
Lantibiotics are ribosomally synthesized, post-translationally modified, peptide antibiotics containing unusual amino acids such as dehydrated amino acids and lanthionine. These unusual amino acids impose conformational constraints on the peptide and contribute to the biological activity and high physicochemical stability of
Wolfgang M Müller et al.
Biochemistry, 50(39), 8362-8373 (2011-09-13)
Lantibiotics are peptide antibiotics, realizing their unique secondary structure by posttranslational modifications, the most important one being the formation of the characteristic amino acid lanthionine. Like other ribosomal peptide antibiotics, they are synthesized with an N-terminal leader peptide important for
Autocrine abscisic acid mediates the UV-B-induced inflammatory response in human granulocytes and keratinocytes.
Bruzzone S, Basile G, Mannino E, et al.
Journal of Cellular Physiology, 227(6), 2502-2510 (2011)
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| L8543-25MG | 04061832726267 |
| L8543-10MG | 04061832726250 |