Application
Lipodisq®与棕榈酰油酰磷脂酰胆碱（POPC）和棕榈酰油酰磷脂酰甘油（POPG）一起可用于纳米颗粒制备。
Lipodisq®试剂是来源于苯乙烯和马来酸的新型聚合物。 Lipodisq聚合物能够形成可在膜蛋白中结合的纳米脂质盘状颗粒。Lipodisq技术可以在不使用表面活性剂的情况下溶解常用的脂质，例如二肉豆蔻酰磷脂酰胆碱（DMPC）。通常，lipodisq聚合物有望用于减少膜蛋白增溶用洗涤剂的使用。在pH 7.4下，Lipodisqs的直径通常为9-10 纳米。
Biochem/physiol Actions
Lipodisq®不含洗涤剂，可用于膜蛋白生物物理研究，包括电子显微镜（EM）、圆二色性（CD）、电子顺磁共振（EPR）和核磁共振（NMR）技术以及递送载体。
Legal Information
Lipodisq is a registered trademark of Malvern Cosmeceutics Limited
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存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
相关内容
Instructions
13 Giant vesicles: A biomimetic tool for assessing membrane material properties and interactions
Characterization and Chemical Modification of the Silica Surface, 415-415 (2019)
Detergent-Free Formation and Physicochemical Characterization of Nanosized Lipid-Polymer Complexes: Lipodisq
Orwick MC, et al.
Angewandte Chemie (International ed. in English), 51(19), 4653-4657 (2012)
Juan Francisco Bada Juarez et al.
Biochimica et biophysica acta. Biomembranes, 1862(3), 183152-183152 (2019-12-18)
Dopamine receptors (DRs) are class A G-Protein Coupled Receptors (GPCRs) prevalent in the central nervous system (CNS). These receptors mediate physiological functions ranging from voluntary movement and reward recognition to hormonal regulation and hypertension. Drugs targeting dopaminergic neurotransmission have been
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| L8920-100MG | 04061833234853 |