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Merck
CN

L9037

L-赖氨酸 一水合物

98.5-101.5% dry basis, suitable for cell culture, BioReagent, non-animal source

别名:

L-Lysine hydrate (1:1), Lysine monohydrate

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关于此项目

经验公式(希尔记法):
C6H14N2O2 · H2O
化学文摘社编号:
分子量:
164.20
NACRES:
NA.26
PubChem Substance ID:
UNSPSC Code:
12352209
EC Number:
200-294-2
MDL number:
Beilstein/REAXYS Number:
4349963
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产品名称

L-赖氨酸 一水合物, BioReagent, suitable for cell culture, from non-animal source

SMILES string

[H]O[H].NCCCC[C@H](N)C(O)=O

InChI

1S/C6H14N2O2.H2O/c7-4-2-1-3-5(8)6(9)10;/h5H,1-4,7-8H2,(H,9,10);1H2/t5-;/m0./s1

InChI key

HZRUTVAFDWTKGD-JEDNCBNOSA-N

biological source

non-animal source

product line

BioReagent

assay

98.5-101.5% dry basis

form

crystalline powder

technique(s)

cell culture | mammalian: suitable

impurities

endotoxin, tested

color

white

mp

215 °C

solubility

H2O: soluble

Quality Level

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Application

L-赖氨酸一水合物已可用于:
  • SILAC(细胞培养中氨基酸稳定同位素标记法)
  • 完全合成(C)培养基,用于酵母细胞的阳性选择筛选
  • 细胞生长培养基

Biochem/physiol Actions

L-赖氨酸是一种必需的蛋白原α氨基酸,广泛应用于多种用途,包括作为非动物来源的细胞培养基中的补充物、L-赖氨酸氧化酶(EC 1.4.3.14)等酶的底物、聚赖氨酸聚合物的组分、氧化和糖基化机理研究的底物。

General description

L-赖氨酸是一种具有碱性侧链的氨基酸,具有两亲性。它有一个质子化的烷基氨基,在生理pH值下完全质子化。L-赖氨酸主要参与蛋白质的静电相互作用。

存储类别

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Daniel Kalb et al.
Chembiochem : a European journal of chemical biology, 16(10), 1426-1430 (2015-05-13)
L-α-Aminoadipic acid reductases catalyze the ATP- and NADPH-dependent reduction of L-α-aminoadipic acid to the corresponding 6-semialdehyde during fungal L-lysine biosynthesis. These reductases resemble peptide synthetases with regard to their multidomain composition but feature a unique domain of elusive function--now referred
W L McKeehan et al.
Proceedings of the National Academy of Sciences of the United States of America, 73(6), 2023-2027 (1976-06-01)
The trace element selenium is essential for clonal growth of diploid fibroblasts from human fetal lung (WI-38) in media containing small amounts of serum protein. Maximum growth stimulation is obtained when 30 nM neutralized selenious acid is added to a
Garrett RH and Grisham CM
Biochemistry (2016)
Shao-En Ong et al.
Nature protocols, 1(6), 2650-2660 (2007-04-05)
Stable isotope labeling by amino acids in cell culture (SILAC) is a simple, robust, yet powerful approach in mass spectrometry (MS)-based quantitative proteomics. SILAC labels cellular proteomes through normal metabolic processes, incorporating non-radioactive, stable isotope-containing amino acids in newly synthesized
Benjamin Newcomb et al.
Methods in molecular biology (Clifton, N.J.), 548, 145-160 (2009-06-13)
A multitude of enzymes that modify histones and remodel nucleosomes are required for the formation, maintenance, and propagation of the transcriptionally repressed chromatin state in eukaryotes. Robust phenotypic screens in yeast S. cerevisiae have proved instrumental in identifying these activities

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