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L9125

L -亮氨酸- p -硝基苯胺

Name: <SC>L </SC>-亮氨酸-<I> p </I>-硝基苯胺
Brand: SIGMA

leucine aminopeptidase substrate, chromogenic, ≥98% (TLC), powder

别名:

L-亮氨酸-4-硝基苯胺

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关于此项目

经验公式（希尔记法）:

C₁₂H₁₇N₃O₃

化学文摘社编号:

4178-93-2

分子量:

251.28

NACRES:

NA.32

PubChem Substance ID:

24896516

UNSPSC Code:

12352204

EC Number:

224-047-3

MDL number:

MFCD00063681

Beilstein/REAXYS Number:

2218433

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属性

产品名称

L -亮氨酸- p -硝基苯胺, leucine aminopeptidase substrate

Quality Level

200

assay

≥98% (TLC)

form

powder

solubility

ethanol: 50 mg/mL

storage temp.

2-8°C

SMILES string

CC(C)C[C@H](N)C(=O)Nc1ccc(cc1)[N+]([O-])=O

InChI

1S/C12H17N3O3/c1-8(2)7-11(13)12(16)14-9-3-5-10(6-4-9)15(17)18/h3-6,8,11H,7,13H2,1-2H3,(H,14,16)/t11-/m0/s1

InChI key

AXZJHDNQDSVIDR-NSHDSACASA-N

说明

General description

用于比色法测定亮氨酸氨肽酶的底物。

Application

L-亮氨酸-p-硝基苯胺用为底物，可用于：

测定虹鳟幼鱼肠道亮氨酸氨基肽酶的活性（虹鳟）
胰岛素调节氨肽酶的抑制分析
测定外肽酶的活性

pictograms

GHS07

signalword

Warning

hcodes

H317,H319

pcodes

P261 - P264 - P272 - P280 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Skin Sens. 1

存储类别

11 - Combustible Solids

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Detection and quantification of leucyl aminopeptidase after native electrophoresis using leucine-p-nitroanilide.

Natasa Bozić et al.

Electrophoresis, 26(12), 2476-2480 (2005-05-28)

A general method for detecting leucyl aminopeptidase activity after native polyacrylamide gel electrophoresis (PAGE) in situ is described. The method is based on diazotization of p-nitroaniline, liberated in the polyacrylamide gel by leucyl aminopeptidase action on leucine-p-nitroanilide (LpNA) and subsequent

Transcription and Activity of Digestive Enzymes of Nezara viridula Maintained on Different Plant Diets.

Pablo Emiliano Cantón et al.

Frontiers in physiology, 10, 1553-1553 (2020-01-24)

Nezara viridula is a polyphagous stink bug that feeds on crops of economic importance such as corn, soybean and cotton. To increase understanding of the ability of this pest insect to feed on such diverse cropping systems, we analyzed the

Poly(ethylene glycol)-poly(lysine) block copolymer-ubenimex conjugate targets aminopeptidase N and exerts an antitumor effect in hepatocellular carcinoma stem cells.

Reishi Toshiyama et al.

Oncogene, 38(2), 244-260 (2018-08-10)

Previous studies highlighted that aminopeptidase N (APN)/CD13 acts as a scavenger in the survival of hepatocellular carcinoma (HCC) stem cells by reducing reactive oxygen species (ROS) levels. Hence, it has been proposed that APN/CD13 inhibition can increase cellular ROS levels

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全球贸易项目编号

货号	GTIN
L9125-500MG	04061833966464
L9125-250MG	04061833966433
L9125-1G	04061833966426
L9125-5G	04061832908960