L9151
Lys-Lys-Lys-Lys-Lys
≥55% peptide basis, Bioreagent
别名:
Lys5, Pentalysine
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关于此项目
经验公式（希尔记法）:
C30H62N10O6
化学文摘社编号:
分子量:
658.88
UNSPSC Code:
12352209
PubChem Substance ID:
NACRES:
NA.26
MDL number:
产品名称
Lys-Lys-Lys-Lys-Lys, ≥55% peptide basis
SMILES string
NCCCCC(N)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(O)=O
InChI
1S/C30H62N10O6/c31-16-6-1-11-21(36)26(41)37-22(12-2-7-17-32)27(42)38-23(13-3-8-18-33)28(43)39-24(14-4-9-19-34)29(44)40-25(30(45)46)15-5-10-20-35/h21-25H,1-20,31-36H2,(H,37,41)(H,38,42)(H,39,43)(H,40,44)(H,45,46)
InChI key
IXPHOHNWDLRFJH-UHFFFAOYSA-N
form
powder
composition
Peptide content, ~60%
concentration
≥55% (peptide)
color
white
storage temp.
−20°C
Biochem/physiol Actions
Short poly-L-lysines polypeptides such as trilysine (lys3), tetralysine (tetra-L-lysine, lys4) and pentalysine (penta-L-lysine, lys5) are cationic moieties that may be used in the construction of gene delivery vectors and DNA nanoparticles.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
常规特殊物品
此项目有
Pentalysine-deoxyribonucleic acid interactions: a model for the general effects of ion concentrations on the interactions of proteins with nucleic acids.
T M Lohman et al.
Biochemistry, 19(15), 3522-3530 (1980-07-22)
Dan Zhao et al.
Journal of neuroinflammation, 14(1), 234-234 (2017-12-05)
It has been shown that chronic stress-induced depression is associated with exaggerated inflammatory response in the brain. Alpha7 nicotinic acetylcholine receptors (α7nAChRs) regulate the cholinergic anti-inflammatory pathway, but the role of cholinergic signaling and α7nAChR in chronic stress has not
M Roux et al.
European biophysics journal : EBJ, 16(5), 267-273 (1988-01-01)
The interaction of cationic pentalysine with phospholipid membranes was studied by using phosphorus and deuterium Nuclear Magnetic Resonance (NMR) of headgroup deuterated dimyristoyl phosphatidylcholine (DMPC) and dimyristoyl phosphatidylserine (DMPS). In the absence of pentalysine, some of the deuterium and phosphorus
Marisa Claudia Alvarez et al.
Clinical epigenetics, 10(1), 139-139 (2018-11-10)
In the present study, we investigated the molecular mechanisms underlying the pro-apoptotic effects of quercetin (Qu) by evaluating the effect of Qu treatment on DNA methylation and posttranslational histone modifications of genes related to the apoptosis pathway. This study was
Fabiana Perocchi et al.
Nucleic acids research, 35(19), e128-e128 (2007-09-28)
Recent transcription profiling studies have revealed an unanticipatedly large proportion of antisense transcription across eukaryotic and bacterial genomes. However, the extent and significance of antisense transcripts is controversial partly because experimental artifacts are suspected. Here, we present a method to
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