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Merck
CN

L9250

亮氨酸-丙氨酸 水合物

Bulk package

别名:

L -亮氨酰- L -丙氨酸 水合物

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关于此项目

线性分子式:
(CH3)2CHCH2CH(NH2)CONHCH(CH3)COOH · xH2O
化学文摘社编号:
分子量:
202.25 (anhydrous basis)
UNSPSC Code:
12352209
NACRES:
NA.26
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
1726165
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Quality Level

assay

≥98% (TLC)

form

powder

technique(s)

ligand binding assay: suitable

color

white

storage temp.

2-8°C

SMILES string

O.CC(C)C[C@H](N)C(=O)N[C@@H](C)C(O)=O

InChI

1S/C9H18N2O3.H2O/c1-5(2)4-7(10)8(12)11-6(3)9(13)14;/h5-7H,4,10H2,1-3H3,(H,11,12)(H,13,14);1H2/t6-,7-;/m0./s1

InChI key

FTDFAGANYJVHDA-LEUCUCNGSA-N

General description

亮氨酰丙氨酸(Leu-Ala)被用于制备非电解三有机锡(IV)衍生物(通式 R3Sn(HL)),以研究金属蛋白相互作用的模型。

Application

亮氨酰丙氨酸 (Leu-Ala) 被用于制备非电解三有机锡 (IV) 衍生物(通式 R3Sn (HL)),以研究金属蛋白相互作用的模型。
以 Leu-Ala 水合物为底物,在三-盐酸(HCl)缓冲液中分析了幼虫中亮氨酸-丙氨酸肽酶(LAP)的活性。

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

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David S Milner et al.
Proceedings of the National Academy of Sciences of the United States of America, 116(12), 5613-5622 (2019-03-08)
Many microbes acquire metabolites in a "feeding" process where complex polymers are broken down in the environment to their subunits. The subsequent uptake of soluble metabolites by a cell, sometimes called osmotrophy, is facilitated by transporter proteins. As such, the
New triorganotin (IV) derivatives of dipeptides as models for metal-protein interactions: synthesis, structural characterization and biological studies.
Nath M, Pokharia S, Eng G, Song X, Kumar A.
Spectrochimica Acta Part A: Molecular Spectroscopy, 63, 66-75 (2006)
Arun K Ghosh et al.
Journal of medicinal chemistry, 50(10), 2399-2407 (2007-04-17)
Structure-based design and synthesis of a number of potent and selective memapsin 2 inhibitors are described. These inhibitors were designed based upon the X-ray structure of memapsin 2-bound inhibitor 3 that incorporates methylsulfonyl alanine as the P2-ligand and a substituted
Arun K Ghosh et al.
Bioorganic & medicinal chemistry letters, 18(3), 1031-1036 (2008-01-09)
Structure-based design, synthesis, and biological evaluation of a series of peptidomimetic beta-secretase inhibitors incorporating hydroxyethylamine isosteres are described. We have identified inhibitor 24 which has shown exceedingly potent activity in memapsin 2 enzyme inhibitory (K(i) 1.8 nM) and cellular (IC(50)=1
Marie Terpager et al.
Journal of receptor and signal transduction research, 29(5), 235-245 (2009-09-15)
7TM receptors are easily fused to proteins such as G proteins and arrestin but because of the fact that their terminals are found on each side of the membrane they cannot be joined directly in covalent dimers. Here, we use

全球贸易项目编号

货号GTIN
L9250-1G04061826685976
L9250-5G04061833966549
L9250-500MG04061833966532

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