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线性分子式:
LiCl
化学文摘社编号:
分子量:
42.39
NACRES:
NA.31
PubChem Substance ID:
UNSPSC Code:
12352302
EC Number:
231-212-3
MDL number:
Assay:
≥99%
Grade:
Molecular Biology
Form:
powder
Solubility:
H2O: 100 mg/mL at 20 °C, clear, colorless
产品名称
氯化锂, Molecular Biology, ≥99%
InChI key
KWGKDLIKAYFUFQ-UHFFFAOYSA-M
InChI
1S/ClH.Li/h1H;/q;+1/p-1
SMILES string
[Li+].[Cl-]
grade
Molecular Biology
assay
≥99%
form
powder
mp
605 °C (lit.)
solubility
H2O: 100 mg/mL at 20 °C, clear, colorless
anion traces
sulfate (SO42-): ≤0.01%
cation traces
Ba: ≤0.003%
Fe: ≤0.001%
K: ≤0.01%
Na: ≤0.20%
heavy metals (as Pb): ≤0.002%
foreign activity
DNase, NICKase, RNase, protease, none detected
Quality Level
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Application
可用于选择性沉淀RNA。
氯化锂已用于:
- 制备染色质免疫沉淀用洗涤缓冲液
- 3-(4,5-二甲基-2-噻唑基)-2,5-二苯基溴化四唑(MTT)检测
- 处理老化成肌细胞,分析其作为糖原合成酶激酶(GSK)抑制剂对于wingless/tailess(wnt)信号传导通路的影响
Biochem/physiol Actions
氯化锂可用于抑制糖原合成酶激酶(GSK)。在无毒性的较低浓度下,它还具有抗炎作用。
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2
存储类别
13 - Non Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
mTOR and neuroinflammation
Molecules to Medicine with mTOR, 317-329 (2016)
Laforin negatively regulates cell cycle progression through glycogen synthase kinase 3beta-dependent mechanisms
Liu R, et al.
Molecular and cellular biology, 28(23), 7236-7244 (2008)
Wnt10b deficiency promotes coexpression of myogenic and adipogenic programs in myoblasts
Vertino AM, et al.
Molecular Biology of the Cell, 16(4), 2039-2048 (2005)
A laboratory practical illustrating the use of the ChIP-qPCR method in a robust model: Estrogen receptor alpha immunoprecipitation using Mcf-7 culture cells
Lacazette E
Biochemistry and Molecular Biology Education, 45(2), 152-160 (2017)
Karla M Acevedo et al.
The Journal of biological chemistry, 289(16), 11007-11019 (2014-03-13)
Amyloid precursor protein (APP) undergoes post-translational modification, including O- and N-glycosylation, ubiquitination, and phosphorylation as it traffics through the secretory pathway. We have previously reported that copper promotes a change in the cellular localization of APP. We now report that
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