生物来源
protein from bovine
质量水平
无菌性
sterile-filtered
产品线
BioReagent
表单
liquid
组成
linoleic acid and oleic acid, 2 mol/mol albumin (each)
浓度
100 mg/mL BSA in DPBS
技术
cell culture | mammalian: suitable
杂质
endotoxin, tested
储存温度
2-8°C
一般描述
脂肪酸-白蛋白复合物在无血清培养基的研制中用作脂质的替代来源。其中脂肪酸以高配比与血清蛋白质相结合。这些蛋白质可以释放有益脂肪酸并结合那些有抑制作用的脂肪酸。油酸与牛血清白蛋白（BSA）结合有利于多种细胞类型（例如幼仓鼠肾 BHK）的生长。多不饱和和单不饱和脂肪酸（如，亚油酸和油酸）在用作培养基补充剂使用时会产生协同效应。
应用
亚油酸-油酸-白蛋白（100x）用于：
- 诱导原代肝细胞中的急性肝细胞应激
- 诱导滋养层细胞中的氧化应激
- 诱导HepG2 细胞中的脂滴积聚
储存分类代码
10 - Combustible liquids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves
法规信息
含少量动物源组分生物产品
此项目有
Pierluigi Ramadori et al.
Free radical biology & medicine, 91, 114-126 (2015-12-25)
Generation of reactive oxygen species (ROS) in response to fatty acids accumulation has been classically proposed as a possible "second hit" triggering progression from simple steatosis to non-alcoholic steatohepatitis (NASH). In this study we challenged hepatocyte-specific Keap1 knockout mice (Keap1(Δhepa))
Laura Moody et al.
Biochimica et biophysica acta. Gene regulatory mechanisms, 1862(2), 141-152 (2019-01-04)
Carnitine palmitoyltransferase 1 (Cpt1a) is a rate-limiting enzyme that mediates the transport of fatty acids into the mitochondria for subsequent beta-oxidation. The objective of this study was to uncover how diet mediates the transcriptional regulation of Cpt1a. Pregnant Sprague Dawley
Anna Virginia Adriana Pirozzi et al.
Antioxidants (Basel, Switzerland), 10(1) (2021-01-06)
Several plant extracts are acquiring increasing value because of their antioxidant activity and hypolipidemic properties. Among them, great interest has been recently paid to açai fruit as a functional food. The aim of this study was to test the ability
Jan Frohlich et al.
Biochimica et biophysica acta. Molecular and cell biology of lipids, 1866(6), 158920-158920 (2021-03-09)
Hepatocellular carcinoma (HCC) is one of the fastest-growing causes of cancer-related mortalities worldwide and this trend is mimicked by the surge of non-alcoholic fatty liver disease (NAFLD). Altered hepatic lipid metabolism promotes HCC development through inflammation and activation of oncogenes.
Yukimasa Takeda et al.
Scientific reports, 10(1), 3775-3775 (2020-03-01)
Brown adipocytes coordinate systemic energy metabolism associated with the pathogenesis of obesity and related metabolic diseases including type 2 diabetes. We have previously reported chemical compound-induced brown adipocytes (ciBAs) converted from human dermal fibroblasts without using transgenes. In this study
商品
Importance and uses of linoleic acid in serum-free eukaryotic, including hybridoma and Chinese Hamster Ovary (CHO) cell, cultures
How the unsaturated fatty acid, oleic acid and other cell culture components affect the performance of serum-free, protein-free cell culture systems used for biomanufacturing heterologous proteins including monoclonal antibodies.
不饱和脂肪酸、油酸和其他细胞培养成分如何影响无血清、无蛋白细胞培养系统（用于生物制造包括单克隆抗体在内的异源蛋白）的性能。
相关内容
Instructions
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持