L9750
Leu-Gly-Gly
别名:
L-leucylglycylglycine, L-Leucyl-glycyl-glycine
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关于此项目
线性分子式:
(CH3)2CHCH2CH(NH2)CONHCH2CONHCH2COOH
化学文摘社编号:
分子量:
245.28
UNSPSC Code:
12352209
NACRES:
NA.26
PubChem Substance ID:
EC Number:
214-698-1
Beilstein/REAXYS Number:
1728928
MDL number:
InChI key
VWHGTYCRDRBSFI-ZETCQYMHSA-N
InChI
1S/C10H19N3O4/c1-6(2)3-7(11)10(17)13-4-8(14)12-5-9(15)16/h6-7H,3-5,11H2,1-2H3,(H,12,14)(H,13,17)(H,15,16)/t7-/m0/s1
SMILES string
CC(C)C[C@H](N)C(=O)NCC(=O)NCC(O)=O
assay
≥98% (TLC)
form
powder
technique(s)
ligand binding assay: suitable
color
white to off-white
storage temp.
−20°C
Gene Information
human ... SLC15A1(6564)
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Biochem/physiol Actions
Leucylglycylglycine (DL-Leu-Gly-Gly) may be used to study the effects of branched-chain di- and tripeptides on cell envelope-associated proteinases (CEPs) activity. L-Leu-Gly-Gly may be used as a substrate to study the kinetics of tripeptide aminopeptidase (EC 3.4.11.4) and other peptidase(s) such as leucylglycylglycine aminopeptidase (EC 3.4.1.3).
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
此项目有
L C Masek et al.
Experimental hematology, 22(12), 1203-1209 (1994-11-01)
"Homing" of hematopoietic progenitor cells to the bone marrow occurs during the clinical practice of bone marrow transplantation. Its mechanism is unknown, although adhesive interactions between hematopoietic cells and sinusoidal endothelium in the bone marrow may be implicated. Studies of
S Kanda et al.
Clinical chemistry, 30(6), 843-846 (1984-06-01)
This is a method for measuring tripeptide aminopeptidase (EC 3.4.11.4) activity in serum. L- Leucylglycylglycine is used as substrate, and the reaction is followed by monitoring the absorbance increase at 340 nm when NAD+ is reduced to NADH in the
María B Espeche Turbay et al.
Journal of agricultural and food chemistry, 57(18), 8607-8611 (2009-09-17)
The cell-envelope-associated proteinase of Lactobacillus delbrueckii subsp. lactis CRL 581 (PrtL) has an essential role in bacterial growth and contributes to the development of the organoleptic properties of hard cheeses and to the release of bioactive health-beneficial peptides from milk
G F Vaeth et al.
Journal of pediatric gastroenterology and nutrition, 1(1), 111-117 (1982-01-01)
The development and distribution of peptidase activity in mucosal homogenates of rat small intestine has been investigated. Substrates used were glycyl-L-leucine (GL), L-seryl-L-methionine (SM), and L-leucyl-glycyl-glycine (LGG). During the first 2 weeks of life there was high peptidase activity toward
T Agatsuma et al.
Parasitology, 91 ( Pt 3), 489-497 (1985-12-01)
An enzyme analysis of diploid and triploid Paragonimus westermani was conducted using starch gel electrophoresis. In total, 16 enzymes, probably encoded by 18 loci, were studied for 3 populations of the diploid form sampled from 2 localities, and 4 populations
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