biological source
equine
Quality Level
form
powder
packaging
pkg of ~15 units/vial
solubility
water: 50 mg/mL, clear to slightly hazy, colorless to faintly yellow
UniProt accession no.
shipped in
ambient
storage temp.
2-8°C
Gene Information
horse ... LHB(100054774), LHCGR(100034043)
Application
Luteinizing hormone (LH) has been used to study effect of LH on the development of preantral follicles for nuclear maturation of ovine oocytes and as an endocrine signal to study circadian phase in the ovary.
Biochem/physiol Actions
Induces ovulation, spermatogenesis, and synthesis of sex steroids.
Two chain glycoprotein hormone, the α-chain is not active, biological specificity is attributed to the β-chain; induces ovulation, spermatogenesis, and synthesis of sex steroids.
Packaging
Package size based on NIH standard LH-S1 using the rat Leydig cell assay
Preparation Note
One NIH LH-S1 unit = approx. 2,000 I.U.
signalword
Danger
hcodes
Hazard Classifications
Repr. 1B
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type P3 (EN 143) respirator cartridges
法规信息
新产品
此项目有
Timing of the Ovarian Circadian Clock Is Regulated by Gonadotropins
Tomoko Y
Endocrinology (2009)
Nuclear maturation of ovine oocytes in cultured preantral follicles
G Tamilmani
The Journal of Small Animal Practice (2005)
Tomoko Yoshikawa et al.
Endocrinology, 150(9), 4338-4347 (2009-06-13)
The timing of ovulation is critically important to the success of reproduction. Current thinking attributes the timing of ovulation to LH secretion by the pituitary, itself timed by signals from the hypothalamus. The discovery of an internal circadian timer in
Rachel Y Cheong et al.
Endocrinology, 155(4), 1418-1427 (2014-01-31)
The negative feedback mechanism through which 17β-estradiol (E2) acts to suppress the activity of the GnRH neurons remains unclear. Using inducible and cell-specific genetic mouse models, we examined the estrogen receptor (ER) isoforms expressed by neurons that mediate acute estrogen
Andrew J Weickhardt et al.
Cancer, 119(13), 2383-2390 (2013-04-16)
Crizotinib is a tyrosine kinase inhibitor active against ALK, MET, and ROS1. We previously reported that crizotinib decreases testosterone in male patients. The detailed etiology of the effect, its symptomatic significance, and the effectiveness of subsequent testosterone replacement have not
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