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Merck
CN

L9879

番茄红素

≥90%, from tomato

别名:

ψ,ψ-胡萝卜素, 2,6,10,14,19,23,27,31-八甲基-三十二烷-2,6,8,10,12,14,16,18,20,22,24,26,30-十三烯

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关于此项目

经验公式（希尔记法）:
C40H56
化学文摘社编号:
502-65-8
分子量:
536.87
UNSPSC Code:
12352200
PubChem Substance ID:
24896530
EC Number:
207-949-1
MDL number:
MFCD00017350

主要文件

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InChI key

OAIJSZIZWZSQBC-GYZMGTAESA-N

InChI

1S/C40H56/c1-33(2)19-13-23-37(7)27-17-31-39(9)29-15-25-35(5)21-11-12-22-36(6)26-16-30-40(10)32-18-28-38(8)24-14-20-34(3)4/h11-12,15-22,25-32H,13-14,23-24H2,1-10H3/b12-11+,25-15+,26-16+,31-17+,32-18+,35-21+,36-22+,37-27+,38-28+,39-29+,40-30+

SMILES string

C\C(C)=C\CC\C(C)=C\C=C\C(C)=C\C=C\C(C)=C\C=C\C=C(C)\C=C\C=C(C)\C=C\C=C(/C)CC\C=C(\C)C

biological source

tomato

assay

≥90%

form

powder

shipped in

dry ice

storage temp.

−70°C

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General description

番茄红素是一种天然产生的红色素，属于类胡萝卜素家族成员。它存在于番茄、西瓜和木瓜中。番茄红素具有抗氧化性。

Application

番茄红素已用于：
  • 通过高效液相色谱(HPLC)测定其在肝、肾和肺组织中的浓度
  • 激活前列腺癌细胞系中的尿激酶型纤溶酶原激活物受体(uPAR)
  • 在拉曼光谱成像中检测和可视化其内分布。

Biochem/physiol Actions

西红柿中的抗氧化剂微量营养素，与降低癌症和心血管疾病风险有关。通过间隙连接蛋白 43 的表达上调促进细胞间间隙连接通讯以及抑制培养中癌细胞增殖。抑制胆固醇合成以及促进低密度脂蛋白降解。

Packaging

密封安瓿瓶装

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
SLCH4654
SLCD6929
SLBX5193
SLBV5371
SLBS4759

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  1. Which document(s) contains shelf-life or expiration date information for a given product?

    If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

  2. How do I get lot-specific information or a Certificate of Analysis?

    The lot specific COA document can be found by entering the lot number above under the "Documents" section.

  3. Is Product L9879, Lycopene, of the Trans or Cis stereoforms?

    Based on the CAS number search in ACS database and the chemicals encyclopedia published by the Royal Society of Chemistry, this lycopene is an all-trans compound. The chemicals encyclopedia published by the Royal Society of Chemistry, 12th ed., Entry# 5650.

  4. What is the method of preparation of Product L9879, Lycopene?

    Details of the method of preparation are considered proprietary information. The last solvent that the lycopene comes into contact with is methanol. However, the material is dried extensively, so little, if any, methanol should be present.

  5. How can Product L9879, Lycopene, be dissolved?

    Lycopene dissolves in carbon disulfide (1 g/50 mL), boiling ether (1 g/3 L), boiling petroleum ether (1 g/12 L) or hexane at 0 °C (1 g/14 L). Lycopene is almost insoluble in methanol or ethanol, but is soluble in chloroform or benzene.

  6. What is the solution stability of Product L9879, Lycopene?

    A solution prepared under argon, protected from light and stored at -20 °C is stable for up to 48 hours.  It is recommended to prepare solutions fresh each time and to prepare immediately before use.

  7. How can I assess the condition of Product L9879, Lycopene, from its appearance?

    We advise against using the product if it becomes speckled or has a "salt and pepper" appearance. An acceptable range of colors is from dark purple to reddish brown to brown.

  8. What is the extinction coefficient of Lycopene, Product L9879?

    Extinction Coefficients: For samples dissolved in petroleum ether, E1% = 3450 (at 472 nm), 2250 (at 446 nm) and 3150 (at 505 nm).

  9. How do I find price and availability?

    There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers.

  10. What is the Department of Transportation shipping information for this product?

    Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product. 

  11. My question is not addressed here, how can I contact Technical Service for assistance?

    Ask a Scientist here.

Lycopene increases urokinase receptor and fails to inhibit growth or connexin expression in a metastatically passaged prostate cancer cell line: a brief communication
Forbes K, et al.
Exp. Biol. Med, 228(8), 967-971 (2003)
Chun-Ming Shih et al.
Polymers, 12(7) (2020-07-15)
Lycopene is the most abundant carotenoid in tomatoes, which has been identified to have the properties of anti-inflammation in addition to the capability to inhibit the expression of adhesion molecules. Intercellular adhesion molecules play a critical role in the pathogenesis
Harris H Wang et al.
Nature, 460(7257), 894-898 (2009-07-28)
The breadth of genomic diversity found among organisms in nature allows populations to adapt to diverse environments. However, genomic diversity is difficult to generate in the laboratory and new phenotypes do not easily arise on practical timescales. Although in vitro
Arnab Chattopadhyay et al.
Journal of lipid research, 54(4), 995-1010 (2013-02-05)
Transgenic tomato plants were constructed with an empty vector (EV) or a vector expressing an apoA-I mimetic peptide, 6F. EV or 6F tomatoes were harvested, lyophilized, ground into powder, added to Western diet (WD) at 2.2% by weight, and fed
An update on the health effects of tomato lycopene
Story EN, et al.
Annual Review of Food Science and Technology, 1, 189-210 (2010)
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