M024080
ssH-Linker
configured for PerkinElmer, configured for Polygen
别名:
9,11-Dioxa-2-aza-10-phosphatridecanoic acid, 10-[bis(1-methylethyl)amino]-13-cyano-, 2-[[(4-methoxyphenyl)diphenylmethyl]amino]ethyl este
登录 查看组织和合同定价。
选择尺寸
关于此项目
经验公式（希尔记法）:
C38H53N4O5P
分子量:
676.83
NACRES:
NA.51
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Assay:
≥98% (31P-NMR), ≥98.0% (reversed phase HPLC)
Storage temp.:
−20°C
InChI
1S/C38H53N4O5P/c1-31(2)42(32(3)4)48(47-29-16-25-39)46-28-15-7-6-14-26-40-37(43)45-30-27-41-38(33-17-10-8-11-18-33,34-19-12-9-13-20-34)35-21-23-36(44-5)24-22-35/h8-13,17-24,31-32,41H,6-7,14-16,26-30H2,1-5H3,(H,40,43)
SMILES string
COc1ccc(cc1)C(NCCOC(=O)NCCCCCCOP(OCCC#N)N(C(C)C)C(C)C)(c2ccccc2)c3ccccc3
InChI key
VTFLXOVDKJUHER-UHFFFAOYSA-N
type
for DNA synthesis
product line
Proligo Reagents
assay
≥98% (31P-NMR), ≥98.0% (reversed phase HPLC)
compatibility
configured for PerkinElmer, configured for Polygen
storage temp.
−20°C
Quality Level
正在寻找类似产品? 访问 产品对比指南
General description
ssH-linker comprises an internal carbamate group attached to the MMT-protected amino group via a short spacer. The carbamate moiety facilitates the cleavage of the MMT group under mildly acidic conditions while increasing the stability of the MMT group during the deprotection of the oligonucleotide with ammonia. The carbamate group also enhances the reactivity of the amino group through a neighbor group effect, and thereby accelerates conjugations to amino reactive modifiers and reporters. The MMT-group of ssH-linker serves as an excellent purification handle after the oligonucleotide synthesis in trityl-on mode, similar to the DMT-group of conventional oligonucleotides. The MMT-group is cleaved under very mild conditions in aqueous acetic acid (10% glacial acetic acid in the water, 20 min. room temp.) Alternatively, the MMT-group can be cleaved on the synthesis instrument with an acidic deblock solution to enable on-support labeling protocols.
Legal Information
This product is covered under US Patent Number 7,491,857
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持