产品名称
黑色素, Synthetic, BioReagent, suitable for cell culture
SMILES string
[nH]1c2c3c(c4c5c([nH]c4)c([c]([c](c5c3c1)=O)=O)C)[c]([c](c2C)=O)=O
InChI key
XUMBMVFBXHLACL-UHFFFAOYSA-N
InChI
1S/C18H10N2O4/c1-5-13-9-7(3-19-13)12-10-8(11(9)17(23)15(5)21)4-20-14(10)6(2)16(22)18(12)24/h3-4,19-20H,1-2H3
biological source
synthetic
product line
BioReagent
assay
≥85% (TLC)
form
powder
technique(s)
cell culture | mammalian: suitable
solubility
1 N NH4OH: 20 mg/mL
storage temp.
−20°C
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Application
黑色素已用于：
- 培养正常人角质形成细胞进行Masson-Fontana染色
- 作为测定正常人表皮黑色素细胞和永生人角质形成细胞中黑色素含量的标准品
- 作为模拟人体皮肤或黑素细胞痣和黑素瘤的吸收剂
Biochem/physiol Actions
黑色素在伪装和能量采集中起着重要作用。它还有助于防止电离紫外线辐射，生物因子防护，如宿主对病原体的防御，以及非生物因素防护，如热，冷和渗透胁迫。黑色素作为一种有效的阳离子螯合剂，因为有利于自由基清除活动，所以是一些光保护霜的组分。黑色素可用作细胞培养物的光保护剂。
General description
黑色素是一种独特的色素，存在于动物、植物、细菌和真菌中。它是由酚类化合物和吲哚类化合物聚合而成的无定形聚合物。
Preparation Note
通过使用过氧化氢对酪氨酸进行氧化制备。
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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