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M042030

Biotin Phosphoramidite

configured for ABI

别名:

Biotin amidite

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关于此项目

经验公式（希尔记法）:
C46H64N5O8PS
化学文摘社编号:
1217500-22-5
分子量:
878.07
NACRES:
NA.21
PubChem Substance ID:
329817780
UNSPSC Code:
41116105
MDL number:
MFCD00676535
Assay:
≥96% (31P-NMR)
Storage temp.:
−20°C
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product line

Proligo Reagents

Quality Segment

200

assay

≥96% (31P-NMR)

suitability

conforms to structure for H-NMR

compatibility

configured for ABI

storage temp.

−20°C

SMILES string

COc1ccc(cc1)C(N2C3CS[C@@H](CCCCC(=O)NCCOCCOCCOP(OCCC#N)N(C(C)C)C(C)C)C3NC2=O)(c4ccccc4)c5ccc(OC)cc5

InChI

1S/C46H64N5O8PS/c1-34(2)51(35(3)4)60(58-27-12-25-47)59-32-31-57-30-29-56-28-26-48-43(52)16-11-10-15-42-44-41(33-61-42)50(45(53)49-44)46(36-13-8-7-9-14-36,37-17-21-39(54-5)22-18-37)38-19-23-40(55-6)24-20-38/h7-9,13-14,17-24,34-35,41-42,44H,10-12,15-16,26-33H2,1-6H3,(H,48,52)(H,49,53)/t41-,42-,44-,60?/m0/s1

InChI key

WSDQYLGSIUJJRU-ZMKGMYJVSA-N

General description

Biotin phosphoramidite is a reagent used to directly incorporate a biotin label at the 5′ hydroxy group of the terminal nucleoside base through a p-aminophenethyl spacer group during oligonucleotide synthesis. Biotin-labelled oligonucleotides have become extremely popular in DNAcapture and detection applications, due to their very high-sensitivity and strong, specific binding affinity with avidin and streptavidin proteins. Biotinbased detection methods and are widely used by researchers. Biotin labelling is compatible with PCR and most hybridization techniques.

Key Features of Biotin Phosphoramidite

  • Behaves like any standard phosphoramidite on the DNA synthesizer
  • Readily soluble in acetonitrile
  • Biotin compound has a dimethoxytrityl (DMT) group on the ring structure,which allows coupling-yield determination and trityl-selective purification
  • A long, water-compatible linker arm ensures maximum sensitivity
  • Provides a coupling efficiency of at least 95%The product is configured for ABI™ Synthesizers

Legal Information

ABI is a trademark of Applera Corporation or its subsidiaries in the US and/or certain other countries

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存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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