方案
≥98% (TLC)
表单
powder
颜色
white
SMILES字符串
CNC(C)C(O)=O
InChI
1S/C4H9NO2/c1-3(5-2)4(6)7/h3,5H,1-2H3,(H,6,7)
InChI key
GDFAOVXKHJXLEI-UHFFFAOYSA-N
生化/生理作用
N-Methyl-DL-alanine may be used in studies of amino acid transport mechanisms such as trans-stimulation. N-Methylalanine may be used in the construction of peptide and protein analogues for use in drug or antibiotic design and development.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
K Lakshminarayana et al.
Indian journal of experimental biology, 38(4), 373-378 (2001-02-24)
Spontaneous mutants resistant to methionine sulfoximine (Msx), methyl alanine (Mal) and methyl ammonium chloride (Mac) were derived from A. chroococcum strain A103. Msx and Mal-resistant mutants expressed 1.73 to 10.98% of the fully derepressed nitrogenase activity when grown in Burk's
G E Mann et al.
The Journal of physiology, 416, 485-502 (1989-09-01)
1. Epithelial uptake and efflux of the non-metabolized system A analogue 2-methylaminoisobutyric acid (MeAIB) and L-serine were studied in the isolated perfused rat pancreas using a dual tracer loading and wash-out technique. Uptakes of 2-[14C]MeAIB and L-[3H]serine were measured relative
Bang-zhi Zhang et al.
Peptides, 31(4), 568-573 (2010-01-05)
The actinomycin D (AMD) analogs in which the D-valine residues (the second amino acid residue in the cyclic depsipeptide of AMD) and the N-methyl-L-valine residues (the fifth amino acid residue in the cyclic depsipeptide of AMD) were replaced with D-Phe
Renata Perlikowska et al.
Basic & clinical pharmacology & toxicology, 106(2), 106-113 (2009-10-31)
A series of endomorphin-1 (EM-1) and endomorphin-2 (EM-2) analogues, containing non-cyclic amino acids (Ala, D-Ala, beta-Ala, NMeAla, D-NMeAla or Sar) instead of Pro in position 2 was synthesized, where NMeAla = N-methylalanine and Sar = N-methylglycine, sarcosine. The opioid activity
D Gazis et al.
International journal of peptide and protein research, 23(1), 78-83 (1984-01-01)
Substituting sarcosine or N-methylalanine for proline in the inhibitory vasopressin analogs dPAVP and d(CH2)5AVP had the following effects: 1) milk ejection and antidiuretic activities were severely depressed, 2) pressor antagonism was maintained but weakened somewhat, and 3) antagonism in the
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