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M0627

7-甲基鸟苷

Name: 7-甲基鸟苷
Brand: SIGMA

≥90%, synthetic, powder

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关于此项目

经验公式（希尔记法）:

C₁₁H₁₅N₅O₅

化学文摘社编号:

20244-86-4

分子量:

297.27

NACRES:

NA.51

PubChem Substance ID:

24896562

UNSPSC Code:

41106305

MDL number:

MFCD16661197

Beilstein/REAXYS Number:

3713683

Assay:

≥90%

Biological source:

synthetic

Form:

powder

Solubility:

water: 50 mg/mL, clear to hazy, colorless to faintly yellow

Storage temp.:

2-8°C

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产品名称

7-甲基鸟苷, ≥90%

biological source

synthetic

Quality Level

200

assay

≥90%

form

powder

solubility

water: 50 mg/mL, clear to hazy, colorless to faintly yellow

storage temp.

2-8°C

SMILES string

C[n+]1cn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c3nc(N)nc([O-])c13

InChI

1S/C11H15N5O5/c1-15-3-16(8-5(15)9(20)14-11(12)13-8)10-7(19)6(18)4(2-17)21-10/h3-4,6-7,10,17-19H,2H2,1H3,(H2-,12,13,14,20)/t4-,6-,7-,10-/m1/s1

InChI key

OGHAROSJZRTIOK-KQYNXXCUSA-N

General description

7-甲基鸟苷结构也称为帽子（cap）。它位于细胞质mRNA的5′末端。

Application

7-甲基鸟苷已被用于去除pre rigor溶液、磷酸盐系统和磷标准溶液中的残留磷酸盐。

Biochem/physiol Actions

7-甲基鸟苷涉及帽依赖性mRNA翻译过程。它也与保护mRNA免于核糖核酸酶的降解有关，并介导核输出。7-甲基鸟苷还允许核糖体的募集。

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Detection of a streptomycin-resistant Mycobacterium bovis strain through antitubercular drug susceptibility testing of Tunisian Mycobacterium tuberculosis complex isolates from cattle.

Saif Eddine Djemal et al.

BMC veterinary research, 14(1), 296-296 (2018-10-01)

A rising isolation trend of drug-resistant M. bovis from human clinical cases is documented in the literature. Here we assessed Mycobacterium tuberculosis complex isolates from cattle for drug susceptibility by the gold standard agar proportion method and a simplified resazurin

The eukaryotic translation initiation factor 4E (eIF4E) as a therapeutic target for cancer

Advances in Protein Chemistry and Structural Biology, 101, 1-26 (2015)

Streamlined purification of fluorescently labeled Escherichia coli phosphate-binding protein (PhoS) suitable for rapid-kinetics applications

Smith D D, et al.

Analytical Biochemistry, 537(10), 106-113 (2017)

The "cap-binding slot" of an mRNA cap-binding protein: quantitative effects of aromatic side chain choice in the double-stacking sandwich with cap.

Guanghui Hu et al.

Biochemistry, 41(24), 7677-7687 (2002-06-12)

The N7-methylguanine portion of the mRNA cap structure interacts with cap-binding proteins via an unusual double-stacking arrangement in which the positively charged cap is sandwiched between two parallel-oriented aromatic protein side chains. Three-dimensional costructures of cap with two mRNA cap-binding

Structure of the yeast tRNA m7G methylation complex.

Nicolas Leulliot et al.

Structure (London, England : 1993), 16(1), 52-61 (2008-01-11)

Loss of N7-methylguanosine (m7G) modification is involved in the recently discovered rapid tRNA degradation pathway. In yeast, this modification is catalyzed by the heterodimeric complex composed of a catalytic subunit Trm8 and a noncatalytic subunit Trm82. We have solved the

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全球贸易项目编号

货号	GTIN
M0627-100MG	04061833993446
M0627-250MG	04061833049648
M0627-25MG	04061833049655

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