M0627
7-甲基鸟苷
≥90%, synthetic, powder
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关于此项目
经验公式(希尔记法):
C11H15N5O5
CAS Number:
分子量:
297.27
Beilstein:
3713683
MDL编号:
UNSPSC代码:
41106305
PubChem化学物质编号:
NACRES:
NA.51
Product Name
7-甲基鸟苷, ≥90%
生物来源
synthetic
质量水平
方案
≥90%
表单
powder
溶解性
water: 50 mg/mL, clear to hazy, colorless to faintly yellow
储存温度
2-8°C
SMILES字符串
C[n+]1cn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c3nc(N)nc([O-])c13
InChI
1S/C11H15N5O5/c1-15-3-16(8-5(15)9(20)14-11(12)13-8)10-7(19)6(18)4(2-17)21-10/h3-4,6-7,10,17-19H,2H2,1H3,(H2-,12,13,14,20)/t4-,6-,7-,10-/m1/s1
InChI key
OGHAROSJZRTIOK-KQYNXXCUSA-N
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一般描述
7-甲基鸟苷结构也称为帽子(cap)。它位于细胞质mRNA的5′末端。
应用
7-甲基鸟苷已被用于去除pre rigor溶液、磷酸盐系统和磷标准溶液中的残留磷酸盐。
生化/生理作用
7-甲基鸟苷涉及帽依赖性mRNA翻译过程。它也与保护mRNA免于核糖核酸酶的降解有关,并介导核输出。7-甲基鸟苷还允许核糖体的募集。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Streamlined purification of fluorescently labeled Escherichia coli phosphate-binding protein (PhoS) suitable for rapid-kinetics applications
Smith D D, et al.
Analytical Biochemistry, 537(10), 106-113 (2017)
The eukaryotic translation initiation factor 4E (eIF4E) as a therapeutic target for cancer
Advances in Protein Chemistry and Structural Biology, 101, 1-26 (2015)
Guanghui Hu et al.
Biochemistry, 41(24), 7677-7687 (2002-06-12)
The N7-methylguanine portion of the mRNA cap structure interacts with cap-binding proteins via an unusual double-stacking arrangement in which the positively charged cap is sandwiched between two parallel-oriented aromatic protein side chains. Three-dimensional costructures of cap with two mRNA cap-binding
Interdomain communication of the Chd1 chromatin remodeler across the DNA gyres of the nucleosome
Nodelman I M, et al.
Molecular Cell, 65(3), 447-459 (2017)
Saif Eddine Djemal et al.
BMC veterinary research, 14(1), 296-296 (2018-10-01)
A rising isolation trend of drug-resistant M. bovis from human clinical cases is documented in the literature. Here we assessed Mycobacterium tuberculosis complex isolates from cattle for drug susceptibility by the gold standard agar proportion method and a simplified resazurin
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