M076000
Sulfur 42
别名:
Phenyl-3H-1,2,4-dithiazol-3-one
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关于此项目
经验公式（希尔记法）:
C8H5NOS2
化学文摘社编号:
分子量:
195.26
NACRES:
NA.03
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
InChI
1S/C8H5NOS2/c10-8-9-7(11-12-8)6-4-2-1-3-5-6/h1-5H
SMILES string
O=C1SSC(C2=CC=CC=C2)=N1
InChI key
LKDWQHQNDDNHSC-UHFFFAOYSA-N
type
for DNA synthesis
product line
Proligo Reagents
assay
≥99.0% (reversed phase HPLC)
form
solid
packaging
pkg of 1 g M076000-1G, 2 g of 2 g M076000-2G
impurities
≤0.1% water content (Karl Fischer)
color
faintly yellow to yellow
solubility
acetonitrile: 0.1 M, clear
suitability
conforms to structure for H-NMR
storage temp.
2-8°C
Quality Level
General description
Sulfur 42 is a sulfurization reagent.
Application
Sulfur 42 is suitable for use instead of an Oxidizer during the synthesis cycle to manufacture thioated oligonucleotides.
Features and Benefits
- Sulfur 42 is at least 4 times more reactive than Beaucage reagent or PADS
- Crystalline powder
- Odourless, no foul smell
- Solubility in ACN up to 0.28M at (+10 °C); no need to applied a co-solvent like in DCM, THF
- The solvent for the dissolution of the reagent should be dry (< 50 ppm) in order to minimize P=O impurities
- Stable in ACN solution for at least 21 days
- Recommended reaction time for the sulfurization in oligonucleotide synthesis for a 0.1M solution is 60 sec
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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