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M0821

莫昔普利 盐酸盐

powder, ≥98% (HPLC)

别名:

(3S)-2-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-3-isoquinolinecarboxylic acid 盐酸盐

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关于此项目

经验公式（希尔记法）:
C27H35N2O7Cl
化学文摘社编号:
82586-52-5
分子量:
535.03
NACRES:
NA.77
PubChem Substance ID:
329817832
UNSPSC Code:
12352200
MDL number:
MFCD00940481
Assay:
≥98% (HPLC)
Form:
powder
Quality level:
100
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Quality Level

100

assay

≥98% (HPLC)

form

powder

solubility

H2O: 32 mg/mL

originator

UCB Inc.

storage temp.

2-8°C

SMILES string

Cl.CCOC(=O)[C@H](CCc1ccccc1)N[C@@H](C)C(=O)N2Cc3cc(OC)c(OC)cc3C[C@H]2C(O)=O

InChI

1S/C27H34N2O7.ClH/c1-5-36-27(33)21(12-11-18-9-7-6-8-10-18)28-17(2)25(30)29-16-20-15-24(35-4)23(34-3)14-19(20)13-22(29)26(31)32;/h6-10,14-15,17,21-22,28H,5,11-13,16H2,1-4H3,(H,31,32);1H/t17-,21-,22-;/m0./s1

InChI key

JXRAXHBVZQZSIC-JKVLGAQCSA-N

Gene Information

human ... ACE(1636)

Biochem/physiol Actions

ACE-Inhibitor; Antihypertensive
Moexipril is an ACE-Inhibitor; Antihypertensive; Unlike other ACE inhibitors, prolongs QT interval leading to torsades de pointes and cardiad arrhythmia;

Features and Benefits

This compound is featured on the Angiotensin Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
This compound was developed by UCB Inc.. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

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pictograms

Environment
GHS09

signalword

Warning

hcodes

H400

Hazard Classifications

Aquatic Acute 1

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000318459
0000303273
0000318459
0000303273
0000137115

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Angiotensin Receptors

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Mila Volchek et al.
Human reproduction (Oxford, England), 25(10), 2455-2464 (2010-08-24)
The mammalian placenta plays a central role in maternal tolerance of the semi-allogeneic fetus and fluid balance between the maternal and fetal compartments. The lymphatics play a role in both these function. The aim of this study was to describe
Thomas S Jacques et al.
The EMBO journal, 29(1), 222-235 (2009-11-21)
It has been suggested that intrinsic brain tumours originate from a neural stem/progenitor cell population in the subventricular zone of the post-natal brain. However, the influence of the initial genetic mutation on the phenotype as well as the contribution of
K E Kristensen et al.
Clinical pharmacology and therapeutics, 96(6), 713-722 (2014-09-16)
Clopidogrel is an oral antiplatelet prodrug, the majority of which is hydrolyzed to an inactive metabolite by hepatic carboxylesterase 1 (CES1). Most angiotensin-converting enzyme inhibitors (ACEIs) are also metabolized by this enzyme. We examined the effects of ACEIs on clopidogrel

全球贸易项目编号

货号GTIN
M0821-100MG04061832898872
M0821-50MG04061832898889