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Merck
CN

M0883

Sigma-Aldrich

4-Methylumbelliferyl acetate

esterase substrate

别名:

MU-Ac

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关于此项目

经验公式(希尔记法):
C12H10O4
化学文摘社编号:
分子量:
218.21
Beilstein:
189667
EC 号:
MDL编号:
UNSPSC代码:
12352204
PubChem化学物质编号:
NACRES:
NA.32
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质量水平

方案

≥98% (TLC)

表单

powder

mp

149-150 °C (lit.)

溶解性

chloroform: 100 mg/mL, clear, colorless

荧光

λex 312 nm in methanol
λex 360 nm; λem 499 nm (Reaction product)

储存温度

−20°C

SMILES字符串

CC(=O)Oc1ccc2C(C)=CC(=O)Oc2c1

InChI

1S/C12H10O4/c1-7-5-12(14)16-11-6-9(15-8(2)13)3-4-10(7)11/h3-6H,1-2H3

InChI key

HXVZGASCDAGAPS-UHFFFAOYSA-N

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象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Latent blue and red fluorophores based on the trimethyl lock.
Luke D Lavis et al.
Chembiochem : a European journal of chemical biology, 7(8), 1151-1154 (2006-06-07)
M L Graber et al.
The American journal of physiology, 250(1 Pt 2), F159-F168 (1986-01-01)
Intracellular pH (pHi) of turtle bladder mucosal cells was studied by the trapped fluorescent indicator technique. Bladders efficiently accumulated and converted 4-methylumbelliferyl acetate to its pH-sensitive derivative 4-methylumbelliferone (4MU). Excited at the pH-indifferent wavelength 334 nm, bladders fluoresced a uniform
Enzyme kinetic studies in cell populations using fluorogenic substrates and flow cytometric techniques.
J V Watson
Cytometry, 1(2), 143-151 (1980-09-01)
H G Raj et al.
Bioorganic & medicinal chemistry, 9(5), 1085-1089 (2001-05-30)
Our earlier work established a convenient assay procedure for acetoxycoumarin (AC): protein transacetylase (TA) by indirectly quantifying the activity of glutathione (GSH)-S-transferase (GST), the extent of inhibition of GST under the conditions of the assay represented TA activity. In this
David Sychantha et al.
Biochemistry, 57(16), 2394-2401 (2018-03-30)
Streptococcus pneumoniae among other Gram-positive pathogens produces O-acetylated peptidoglycan using the enzyme OatA. This process occurs through the transfer of an acetyl group from a donor to the hydroxyl group of an acceptor sugar. While it has been established that

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