M0905
4-Methylumbelliferyl β-D-mannopyranoside
≥98% (TLC), powder
别名:
4-Methylumbelliferyl β-D-mannoside
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关于此项目
经验公式（希尔记法）:
C16H18O8
化学文摘社编号:
分子量:
338.31
UNSPSC Code:
12352204
PubChem Substance ID:
NACRES:
NA.32
MDL number:
产品名称
4-Methylumbelliferyl β-D-mannopyranoside, ≥98% (TLC)
SMILES string
CC1=CC(=O)Oc2cc(O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]3O)ccc12
InChI
1S/C16H18O8/c1-7-4-12(18)23-10-5-8(2-3-9(7)10)22-16-15(21)14(20)13(19)11(6-17)24-16/h2-5,11,13-17,19-21H,6H2,1H3/t11-,13-,14+,15+,16-/m1/s1
InChI key
YUDPTGPSBJVHCN-NZBFACKJSA-N
assay
≥98% (TLC)
form
powder
solubility
pyridine: 10 mg/mL, clear, colorless to faintly yellow
storage temp.
−20°C
Quality Level
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Application
4-Methylumbelliferyl β-D-mannopyranoside has been used as a fluorogenic substrate for β -mannosidase in the enzyme assay of mice tissue extracts, in cell-free translation and midgut of Lutzomyia longipalpis.
Biochem/physiol Actions
4-Methylumbelliferyl β-D-mannopyranoside is a fluorescent ligand for concanavalin A and interacts with its carbohydrate binding region. It is also a fluorogenic substrate for β-mannosidase.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
涉药品监管产品
此项目有
Taichi E Takasuka et al.
Methods in molecular biology (Clifton, N.J.), 1118, 71-95 (2014-01-08)
In nature, bacteria and fungi are able to utilize recalcitrant plant materials by secreting a diverse set of enzymes. While genomic sequencing efforts offer exhaustive lists of genes annotated as potential polysaccharide-degrading enzymes, biochemical and functional characterizations of the encoded
B T Adams et al.
Chemical communications (Cambridge, England), 51(57), 11390-11393 (2015-06-19)
β-Glucocerebrosidase deficiency leads to Gaucher disease and is a potential marker of Parkinson's disease. We have identified N-octyl conduritol aziridine as a potent and specific covalent inactivator of GBA1 in living cells. This compound is a promising lead towards a
C S Moraes et al.
Journal of insect physiology, 58(8), 1136-1145 (2012-06-12)
The sandfly Lutzomyia longipalpis (Lutz and Neiva, 1912) is the main vector of American Visceral Leishmaniasis. In spite of its medical importance and several studies concerning adult digestive physiology, biochemistry and molecular biology, very few studies have been carried out
Mei Zhu et al.
Human molecular genetics, 15(3), 493-500 (2005-12-27)
Beta-mannosidase, a lysosomal enzyme which acts exclusively at the last step of oligosaccharide catabolism in glycoprotein degradation, functions to cleave the unique beta-linked mannose sugar found in all N-linked oligosaccharides of glycoproteins. Deficiency of this enzyme results in beta-mannosidosis, a
H E Auer et al.
International journal of peptide and protein research, 24(5), 462-471 (1984-11-01)
Properties characteristic of the structure and function of dimeric concanavalin A have been studied as a function of pH in the acid pH range using preparations comprising intact subunits or enriched in fragmented chains. For intact subunits, the glycogen binding
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