M1275
萘普生 钠
synthetic (organic), 98.0-102.0%, Prostaglandin H synthase 1 and 2 inhibitor, powder
别名:
(S)-6-甲氧基-α-甲基-2-萘乙酸 钠盐
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关于此项目
经验公式（希尔记法）:
C14H13NaO3
化学文摘社编号:
分子量:
252.24
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
247-486-2
MDL number:
Assay:
98.0-102.0%
Form:
powder
产品名称
萘普生 钠, 98.0-102.0%
biological source
synthetic (organic)
Quality Segment
assay
98.0-102.0%
form
powder
solubility
water: 100 mg/mL, clear to slightly hazy, colorless to faintly yellow
originator
Bayer
SMILES string
[Na+].COc1ccc2cc(ccc2c1)[C@H](C)C([O-])=O
InChI
1S/C14H14O3.Na/c1-9(14(15)16)10-3-4-12-8-13(17-2)6-5-11(12)7-10;/h3-9H,1-2H3,(H,15,16);/q;+1/p-1/t9-;/m0./s1
InChI key
CDBRNDSHEYLDJV-FVGYRXGTSA-M
Gene Information
human ... PTGS1(5742), PTGS2(5743)
General description
萘普生属于苯乙酸类非甾体抗炎药 (NSAID)。
Biochem/physiol Actions
萘普生最好与血清白蛋白结合。与 R-异构体相比，萘普生的 S-异构体作为抗炎药物的潜力是前者的 28 倍。发现 R-异构体是一种肝脏毒素，可导致胃肠道疾病。
环加氧酶（前列腺素 H 合成酶 1 和 2）抑制剂。
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signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Repr. 1A
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
ppe
dust mask type N95 (US), Eyeshields, Gloves