一般描述
The TEPC-183 tumor line that produces mouse IgM is a tetramethylpentadecane (pristane) induced plasmacytoma, originated and carried intraperitoneally in BALB/c mice. Mouse consists of five immunoglobulin classes- IgM, IgG, IgA, IgD and IgE. IgM is present on the surface of B lymphocytes in its monomeric form.
应用
IgM, Kappa from murine myeloma has been used as a control to study its effects on brain derived synaptic plasticity.
生化/生理作用
IgM antibodies are present as pentamers in serum and are produced in response to antigens.
制备说明
Reconstitute with 1 ml deionized water.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
法规信息
常规特殊物品
M Lohoff et al.
Infection and immunity, 56(8), 2120-2124 (1988-08-01)
The well-established polyclonal B-cell stimulation in the lymphoid organs in mice infected with Leishmania major is thought to be dependent on T cells. Here we present clear experimental evidence that this is indeed the case by showing that BALB/c-derived, L3T4-positive
Molecular Genetics of Immunoglobulin, 17 (1987)
A monoclonal antibody against synthetic A beta dimer assemblies neutralizes brain-derived synaptic plasticity-disrupting A beta
ONuallain B, et al.
Journal of Neurochemistry, 119(1), 189-201 (2011)
The Immunoglobulins: Structure and Function (1998)
D M Reinitz et al.
Infection and immunity, 58(7), 2337-2342 (1990-07-01)
The T-cell dependency of B-cell responses to variant surface glycoprotein (VSG) epitopes exposed in their native surface conformation on Trypanosoma brucei rhodesiense clone LouTat 1 was investigated. T-cell requirements were examined by analyses of gamma globulin preparations derived from trypanosome-infected
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