M2015
1-硬脂酰- rac -甘油
≥99%
别名:
MG(18:0/0:0/0:0)[rac], 1-单十八烷酰- rac -甘油, rac -甘油 1-硬脂酸酯, DL -α-硬脂, 甘油一硬脂酸酯
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线性分子式:
CH3(CH2)16COOCH2CH(OH)CH2OH
化学文摘社编号:
分子量:
358.56
UNSPSC Code:
51191904
NACRES:
NA.25
PubChem Substance ID:
EC Number:
204-664-4
Beilstein/REAXYS Number:
1728685
MDL number:
产品名称
1-硬脂酰- rac -甘油, ≥99%
form
powder
InChI key
VBICKXHEKHSIBG-UHFFFAOYSA-N
InChI
1S/C21H42O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(24)25-19-20(23)18-22/h20,22-23H,2-19H2,1H3
SMILES string
CCCCCCCCCCCCCCCCCC(=O)OCC(O)CO
biological source
synthetic (organic)
assay
≥99%
functional group
phospholipid
lipid type
neutral glycerides
shipped in
ambient
storage temp.
−20°C
Quality Level
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Application
单硬脂酸甘油酯 (1-Stearoyl-rac-glycerol) 用于纳米颗粒和微乳剂等药物传递载体的开发。
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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International journal of pharmaceutics, 532(1), 612-622 (2017-09-25)
The oral uptake of intact nanocarriers through Peyer's patches is an important uptake pathway. We report Rifampicin Lipid-Polymer hybrid nanoparticles (RIF-LIPOMER) using glyceryl monostearate as lipid and the mucoadhesive polymer, Gantrez, with the objective of balancing hydrophobicity and mucoadhesion for
Maria Christina Camasmie Peters et al.
Journal of drug targeting, 28(3), 259-270 (2019-09-07)
Nanocrystals and lipid-based nanosystems have the potential to play a crucial role in a significant shift in the treatment of ophthalmic diseases. These drug delivery systems allow overcoming the barriers imposed by anatomy and physiology of the organ of vision.
Howida Kamal Ibrahim et al.
Drug delivery, 23(9), 3181-3192 (2016-03-05)
Statins proved potential bone healing properties. Rosuvastatin is a synthetic, hydrophilic, potent and highly efficacious statin. In the current work, an attempt was investigated to develop, evaluate various bioerodible composite sponges enclosing rosuvastatin and explore their potential in augmenting bone
Mitali H Patel et al.
Drug development and industrial pharmacy, 45(8), 1242-1257 (2019-03-19)
Objective: The aim of the present investigation was to investigate the efficacy of solid lipid nanoparticles (SLNs) to enhance the absorption and bioavailability of lurasidone hydrochloride (LH) following oral administration. Methods: The LH loaded SLNs (LH-SLNs) were prepared by high
Maria Chountoulesi et al.
Brain sciences, 10(6) (2020-06-06)
Multiple sclerosis (MS) is a chronic, autoimmune, neurodegenerative disease of the central nervous system (CNS) that yields to neuronal axon damage, demyelization, and paralysis. Although several drugs were designed for the treatment of MS, with some of them being approved
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