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M212

Mastoparan-7

Name: Mastoparan-7
Brand: SIGMA

≥97% (HPLC), lyophilized powder

别名:

Mas 7

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经验公式（希尔记法）:

C₆₇H₁₂₄N₁₈O₁₅

化学文摘社编号:

145854-59-7

分子量:

1421.81

NACRES:

NA.77

PubChem Substance ID:

329817929

UNSPSC Code:

41106300

MDL number:

MFCD00144726

Assay:

≥97% (HPLC)

Form:

lyophilized powder

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属性

Quality Segment

200

assay

≥97% (HPLC)

form

lyophilized powder

storage temp.

−20°C

SMILES string

CC[C@H](C)[C@H](N)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(N)=O

InChI

1S/C67H124N18O15/c1-18-38(12)53(71)67(100)85-51(32-52(70)86)66(99)84-50(31-37(10)11)64(97)79-45(24-20-22-26-69)61(94)75-42(16)58(91)82-47(28-34(4)5)62(95)76-39(13)55(88)73-40(14)57(90)81-48(29-35(6)7)63(96)77-41(15)56(89)78-44(23-19-21-25-68)60(93)74-43(17)59(92)83-49(30-36(8)9)65(98)80-46(54(72)87)27-33(2)3/h33-51,53H,18-32,68-69,71H2,1-17H3,(H2,70,86)(H2,72,87)(H,73,88)(H,74,93)(H,75,94)(H,76,95)(H,77,96)(H,78,89)(H,79,97)(H,80,98)(H,81,90)(H,82,91)(H,83,92)(H,84,99)(H,85,100)/t38-,39-,40-,41-,42-,43-,44-,45-,46-,47-,48-,49-,50-,51-,53-/m0/s1

InChI key

HOLQXBRPSSZJMZ-FGRXCANLSA-N

说明

General description

Mastoparan-7 is an analog of the mastoparan peptide. It is present in the venom of Vespula lewisii. It was originally isolated from wasp venom.

Application

Mastoparan-7 has been used to study mastoparan-stimulated nucleotide binding to G proteins.

Biochem/physiol Actions

Mastoparan-7 (Mas-7) stimulates the G protein subunit Gα_o/i by its mode of action (to bind to the plasma membrane). It possesses antiviral activity and is associated with histamine release from mast cells. It is also involved in the induction of potent mitochondrial permeability and tumor cell cytotoxicity.

Analysis Note

More potent analog of mastoparan.

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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全球贸易项目编号

货号	GTIN
M212-1MG	04061826675977