M2140
1-癸酰基-rac-甘油
≥99%
别名:
单辛
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关于此项目
经验公式（希尔记法）:
C13H26O4
化学文摘社编号:
分子量:
246.34
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
12352211
EC Number:
247-667-6
MDL number:
InChI key
LKUNXBRZDFMZOK-UHFFFAOYSA-N
InChI
1S/C13H26O4/c1-2-3-4-5-6-7-8-9-13(16)17-11-12(15)10-14/h12,14-15H,2-11H2,1H3
SMILES string
O=C(OCC(O)CO)CCCCCCCCC
biological source
synthetic (organic)
assay
≥99%
form
powder
functional group
ketone
lipid type
neutral glycerides
shipped in
ambient
storage temp.
−20°C
Quality Level
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Application
- Novel LC/MS/MS and High-Throughput Mass Spectrometric Assays for Monoacylglycerol Acyltransferase Inhibitors.：该文提供筛选单酰基甘油酰基转移酶抑制剂的先进分析方法，对于代谢疾病治疗有重要意义。1-癸酰-外消旋甘油在研究中是重要的化合物(Qi J et al., 2017)。
- Optimized reverse micelle surfactant system for high-resolution NMR spectroscopy of encapsulated proteins and nucleic acids dissolved in low viscosity fluids.：该文描述了一种使用1-癸酰-外消旋甘油的新型表面活性剂系统，可改进蛋白与核酸的核磁共振波谱(NMR)分析，使分辨率更高、粘度降低(Dodevski I et al., 2014)。
Biochem/physiol Actions
一癸酸甘油酯（单癸酸甘油酯）用于开发对包膜病毒、某些酵母菌和细菌（例如白色念珠菌和弯曲杆菌）具有活性的抗菌消毒剂。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Skuli Skulason et al.
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 41(1), 61-67 (2011-05-04)
Current treatment of herpes labialis is usually with topical antiviral drugs and early drug administration is required for effectiveness. Monocaprin, a 1-monoglyceride of capric acid, has high microbicidal activity in vitro and efficiently inactivates herpes simplex virus. Tetracyclines are inhibitors
Thórunn O Thorgeirsdóttir et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 59(2), 333-342 (2005-01-22)
The purpose of this study was to characterize the rheological and structural properties of a pharmaceutical multicomponent hydrogel formulation. This formulation consists of a hydrogel-forming poly(acrylic acid) polymer (Carbopol 974P), microbicide (monocaprin), non-ionic surfactant (Tween 20 or Tween 40), and
P Reis et al.
Langmuir : the ACS journal of surfaces and colloids, 22(19), 8169-8177 (2006-09-06)
Starting from gold chips, we have tailor-made three surfaces by the self-assembly monolayer technique: one entirely hydrophobic, one hydrophobic with dispersed carboxyl groups, and one hydrophilic, containing hydroxyl groups. Rhizomucor miehei lipase has been adsorbed to the hydrophobic and the
J R Brown et al.
International journal of pharmaceutics, 245(1-2), 133-142 (2002-09-25)
This study explores the potential of the monoglyceride monocaprin as an enhancer of the epithelial permeability of the beta(3)-adrenoceptor agonist BTA-243, as an approach to improving the bioavailability of this drug. The permeabilities of BTA-243 and mannitol (paracellular marker) in
G Bergsson et al.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica, 109(10), 670-678 (2002-03-14)
The susceptibilities of three Gram-positive cocci to medium-chain saturated and long-chain unsaturated fatty acids and their one-monoglycerides were studied. The bacteria were incubated with equal volumes of lipid solutions for 10 min. Lauric acid, palmitoleic acid and monocaprin reduced the
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