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Merck
CN

M2265

Sigma-Aldrich

1-辛酰- rac -甘油

≥99%

别名:

1-辛酰- rac -甘油, 野百合碱

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关于此项目

经验公式(希尔记法):
C11H22O4
化学文摘社编号:
分子量:
218.29
MDL编号:
UNSPSC代码:
12352211
PubChem化学物质编号:
NACRES:
NA.25
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质量水平

方案

≥99%

表单

powder

官能团

ester

脂质类型

neutral glycerides

运输

ambient

储存温度

−20°C

SMILES字符串

CCCCCCCC(=O)OCC(O)CO

InChI

1S/C11H22O4/c1-2-3-4-5-6-7-11(14)15-9-10(13)8-12/h10,12-13H,2-9H2,1H3

InChI key

GHBFNMLVSPCDGN-UHFFFAOYSA-N

应用


  • 群体感应调节因子的分子模拟和马尔可夫态建模:研究揭示了大肠杆菌中群体感应调节因子SdiA的非活性形式,为研究可能受到1-辛酰-rac-甘油等脂质信号分子影响的细菌通讯机制提供了见解(Grabski et al., 2021)。

生化/生理作用

辛酸甘油酯(1-辛酰-rac-甘油)是一种抗菌单甘酯,可以治疗刚果放线菌和弯曲杆菌感染以及灭活生物表面上 大肠杆菌 李斯特菌 沙门氏菌

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Preeti Wavikar et al.
Journal of pharmaceutical sciences, 106(12), 3613-3622 (2017-09-20)
Present investigation explores the potential of nanostructured lipid carriers (NLCs) for nose to brain delivery of rivastigmine (RV), which is further enhanced by incorporating into an in situ gelling system, increasing retention in nasal cavity. NLCs having particle size of
Varun Garg et al.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 109, 297-315 (2017-08-27)
Development of self-nanoemulsifying drug delivery systems (SNEDDS) of polypeptide-k (PPK) is reported with the aim to achieve its oral delivery. Box-Behnken design (BBD) was adopted to develop and optimize the composition of SNEDDS. Oleoyl polyoxyl-6 glycerides (A), Tween 80 (B)
Abdulsalam M Kassem et al.
Journal of microencapsulation, 34(3), 319-333 (2017-05-10)
The objective of this study was to develop and optimise self-nanoemulsifying drug delivery system (SNEDDS) of atorvastatin calcium (ATC) for improving dissolution rate and eventually oral bioavailability. Ternary phase diagrams were constructed on basis of solubility and emulsification studies. The
Dong Woo Yeom et al.
Oncotarget, 8(55), 94297-94316 (2017-12-08)
In order to improve the dissolution and oral bioavailability of valsartan (VST), and reduce the required volume for treatment, we previously formulated a supersaturable self-microemulsifying drug delivery system (SuSMEDDS) composed of VST (80 mg), Capmul
Dong Jun Shin et al.
Pharmaceutics, 11(2) (2019-02-03)
To improve the dissolution and oral bioavailability of valsartan (VST), we previously formulated a supersaturable self-microemulsifying drug delivery system (SuSMED) composed of Capmul® MCM (oil), Tween® 80 (surfactant), Transcutol® P (cosurfactant), and Poloxamer 407 (precipitation inhibitor) but encountered a stability

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