产品名称
髓鞘碱性蛋白 来源于天竺鼠大脑, ≥80% (SDS-PAGE), lyophilized powder, from guinea pig brain
biological source
guinea pig brain
assay
≥80% (SDS-PAGE)
form
lyophilized powder
technique(s)
cell based assay: suitable
UniProt accession no.
application(s)
cell analysis
storage temp.
−20°C
Quality Level
Gene Information
guinea pig ... MBP(100731253)
Analysis Note
可能含有微量尿素-甘氨酸缓冲液盐。
Application
豚鼠脑髓鞘碱性蛋白在以下应用中用作激酶底物：分析体外激酶活性，蛋白质磷酸化分析，ATG1激酶测定
Biochem/physiol Actions
CNS 髓磷脂的主要结构蛋白。用于诱导实验性过敏性脑脊髓炎。
用作激酶底物。
髓磷脂碱性蛋白（MBP）在髓鞘的形成中起重要作用，并且与各种神经障碍有关。髓磷脂碱性蛋白作为自身免疫疾病实验性变应性脑脊髓炎（EAE）中的抗原靶标起作用。髓磷脂碱性蛋白在细胞骨架更新和膜延伸中起重要作用。此外，它还参与 Fyn 介导的信号途径、磷酸肌醇的隔离和钙稳态的调节。髓磷脂碱性蛋白作为丝裂原活化蛋白激酶（MAP）激酶的体外底物起作用，并有助于酶的纯化和功能研究。
髓鞘碱性蛋白基因的突变诱导髓鞘形成；用于诱导实验性过敏性脑脊髓炎。
General description
在豚鼠脑中表达的髓鞘碱性蛋白（MBP）含有 167 个氨基酸，分子量为 18,256Da。
研究领域：细胞信号传导髓鞘碱性蛋白（MBP）是CNS（中枢神经系统）髓鞘的重要组成部分。它是一种自身免疫原。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
低风险生物材料
此项目有
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