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Merck
CN

M2381

Sigma-Aldrich

5-Methoxy-N,N-dimethyltryptamine

别名:

3-(2-Dimethylaminoethyl)-5-methoxyindole, 3-[2-(Dimethylamino)ethyl]-5-methoxyindole, 5-MeO-DMT, 5-Methoxy-DMT, 5-OMe-DMT

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关于此项目

经验公式（希尔记法）:
C13H18N2O
化学文摘社编号:
1019-45-0
分子量:
218.29
EC 号:
213-813-2
MDL编号:
MFCD00005658
UNSPSC代码:
41116107
PubChem化学物质编号:
24278119

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药品控制

USDEA Schedule I; Home Office Schedule 1; kontrollierte Droge in Deutschland

mp

69-70 °C (lit.)

储存温度

2-8°C

SMILES字符串

COc1ccc2[nH]cc(CCN(C)C)c2c1

InChI

1S/C13H18N2O/c1-15(2)7-6-10-9-14-13-5-4-11(16-3)8-12(10)13/h4-5,8-9,14H,6-7H2,1-3H3

InChI key

ZSTKHSQDNIGFLM-UHFFFAOYSA-N

基因信息

human ... HTR1A(3350), HTR1B(3351), HTR1D(3352), HTR1E(3354), HTR1F(3355), HTR2A(3356), HTR2B(3357), HTR2C(3358), HTR3A(3359), HTR3B(9177), HTR3C(170572), HTR3D(200909), HTR3E(285242), HTR4(3360), HTR5A(3361), HTR5B(645694), HTR6(3362), HTR7(3363)
rat ... Htr1a(24473), Htr2a(29595), Htr2b(29581), Htr2c(25187), Htr7(65032)

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生化/生理作用

Hallucinogen; non-selective serotonin receptor agonist.

象形图

Exclamation mark
GHS07

警示用语：

Warning

危险声明

H336

危险分类

STOT SE 3

靶器官

Central nervous system

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
BCBJ1656V
040M1491V
040M1491
1434914
1434915

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Adam L Halberstadt
Pharmacology, biochemistry, and behavior, 143, 1-10 (2016-01-19)
Monoamine oxidase inhibitors (MAOIs) are often ingested together with tryptamine hallucinogens, but relatively little is known about the consequences of their combined use. We have shown previously that monoamine oxidase-A (MAO-A) inhibitors alter the locomotor profile of the hallucinogen 5-methoxy-N,N-dimethyltryptamine
Rafael Vitor Lima da Cruz et al.
Frontiers in molecular neuroscience, 11, 312-312 (2018-09-21)
The subgranular zone (SGZ) of dentate gyrus (DG) is one of the few regions in which neurogenesis is maintained throughout adulthood. It is believed that newborn neurons in this region encode temporal information about partially overlapping contextual memories. The 5-Methoxy-N,N-dimethyltryptamine
Vanja Dakic et al.
Scientific reports, 7(1), 12863-12863 (2017-10-11)
Dimethyltryptamines are entheogenic serotonin-like molecules present in traditional Amerindian medicine recently associated with cognitive gains, antidepressant effects, and changes in brain areas related to attention. Legal restrictions and the lack of adequate experimental models have limited the understanding of how
Jessica Winne et al.
Experimental neurology, 326, 113175-113175 (2020-01-11)
Salicylate intoxication is a cause of tinnitus and comorbidly associated with anxiety in humans. In a previous work, we showed that salicylate induces anxiety-like behavior and hippocampal type 2 theta oscillations (theta2) in mice. Here we investigate if the anxiogenic
Thomas S Ray
PloS one, 5(2), e9019-e9019 (2010-02-04)
We currently understand the mental effects of psychedelics to be caused by agonism or partial agonism of 5-HT(2A) (and possibly 5-HT(2C)) receptors, and we understand that psychedelic drugs, especially phenylalkylamines, are fairly selective for these two receptors. This manuscript is
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