M2672
(±)-α-Methyl-(4-tetrazolylphenyl)glycine
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About This Item
经验公式（希尔记法）:
C10H11N5O2
CAS Number:
分子量:
233.23
MDL编号:
UNSPSC代码:
12352202
PubChem化学物质编号:
表单
solid
储存温度
2-8°C
SMILES字符串
CC(N)(C(O)=O)c1ccc(cc1)-n2cnnn2
InChI
1S/C10H11N5O2/c1-10(11,9(16)17)7-2-4-8(5-3-7)15-6-12-13-14-15/h2-6H,11H2,1H3,(H,16,17)
InChI key
PUQSGMIEFYCTSW-UHFFFAOYSA-N
生化/生理作用
(±)-α-Methyl-(4-tetrazolylphenyl)glycine (MTPG) was used in rat models of cerebral ischemia to explore the role of group II metabotropic glutamate receptors mGluR2/3 in brain ischemia tolerance. MTPG inhibited the induction of ischemia tolerance indicating the involvement of mGluR2/3 in the induction of the protective mechanism.
Potent antagonist for (1S,3S)-ACPD-sensitive receptors; preference for GluR2 and GluR3 subtypes
储存分类代码
13 - Non Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
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