主要文件

查看所有文档

M2901

吗多明

Name: 吗多明
Brand: SIGMA

别名:

N-(Ethoxycarbonyl)-3-(4-morpholino)sydnone imine, SIN-10

登录查看组织和合同定价。

选择尺寸

变更视图

关于此项目

经验公式（希尔记法）:

C₉H₁₄N₄O₄

化学文摘社编号:

25717-80-0

分子量:

242.23

NACRES:

NA.77

PubChem Substance ID:

24278544

UNSPSC Code:

12352200

EC Number:

247-207-4

MDL number:

MFCD00869301

技术服务

需要帮助？我们经验丰富的科学家团队随时乐意为您服务。

让我们为您提供帮助

属性

storage temp.

2-8°C

SMILES string

CCOC(=O)N=C1O[N-][N+](=C1)N2CCOCC2

InChI

1S/C9H14N4O4/c1-2-16-9(14)10-8-7-13(11-17-8)12-3-5-15-6-4-12/h7H,2-6H2,1H3/b10-8-

InChI key

XLFWDASMENKTKL-NTMALXAHSA-N

说明

Application

Molsidomine has been used as nitric oxide (NO)-releasing vasodilator to study the effect of NO on angiostatin production in aging rat kidneys.

Biochem/physiol Actions

Molsidomine is an effective vasodilator and a long-lasting nitric oxide (NO) donor. It is a pro-drug that is enzymatically decarboxylated to form 3-morpholinosydnone imine (SIN-1) in the liver. Molsidomine is used as an anti-anginal agent and possesses antioxidant properties. It may be used to treat cisplatin-induced oxidative stress in the liver tissue. Molsidomine has also been used during angina pectoris, heart failure, and after myocardial infarction.

Orally active, long acting vasodilator; antianginal; converted by the liver to the active metabolite, SIN-1

Still not finding the right product?

Explore all of our products under 吗多明

pictograms

GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

存储类别

11 - Combustible Solids

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Gloves

法规信息

新产品

此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

没有发现合适的版本？

如果您需要特殊版本，可通过批号或批次号查找具体证书。

搜索COA

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

Molsidomine

Meyler's Side Effects of Drugs: The International Encyclopedia of Adverse Drug Reactions and Interactions (2016)

Molsidomine: alternative approaches to treat myocardial ischemia.

R E Nitz et al.

Pharmacotherapy, 7(1), 28-37 (1987-01-01)

The long-acting antianginal drug molsidomine has been shown experimentally to reduce myocardial infarct size when administered prior to or after cardiac insult. This is due to several drug actions. Dilation of postcapillary capacitance vessels diminishes venous return, preload, heart dimensions

Nitric oxide sustains long-term skeletal muscle regeneration by regulating fate of satellite cells via signaling pathways requiring Vangl2 and cyclic GMP.

Roberta Buono et al.

Stem cells (Dayton, Ohio), 30(2), 197-209 (2011-11-16)

Satellite cells are myogenic precursors that proliferate, activate, and differentiate on muscle injury to sustain the regenerative capacity of adult skeletal muscle; in this process, they self-renew through the return to quiescence of the cycling progeny. This mechanism, while efficient

查看所有相关文献

全球贸易项目编号

货号	GTIN
M2901-5G	04061833428528
M2901-500MG	04061833435120