跳转至内容
Merck
CN

M2939

甲基花生四烯酸氟磷酸酯

≥98%, calcium-dependent and calcium-independent cytosolic phospholipase A2 inhibitor, methyl acetate solution (10 mg/mL)

别名:

MAPF, 甲基-5Z,8Z,11Z,14Z-二十碳四烯酸酯

登录 查看组织和合同定价。

选择尺寸


关于此项目

经验公式(希尔记法):
C21H36FO2P
化学文摘社编号:
分子量:
370.48
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
41106300
EC Number:
201-185-2
MDL number:
Assay:
≥98%
Form:
methyl acetate solution (10 mg/mL)
Quality level:
技术服务
需要帮助?我们经验丰富的科学家团队随时乐意为您服务。
让我们为您提供帮助
技术服务
需要帮助?我们经验丰富的科学家团队随时乐意为您服务。
让我们为您提供帮助

产品名称

甲基花生四烯酸氟磷酸酯, ≥98%, methyl acetate solution (10 mg/mL)

InChI key

KWKZCGMJGHHOKJ-ZKWNWVNESA-N

InChI

1S/C21H36FO2P/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-25(22,23)24-2/h7-8,10-11,13-14,16-17H,3-6,9,12,15,18-21H2,1-2H3/b8-7-,11-10-,14-13-,17-16-

SMILES string

CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCCP(F)(=O)OC

assay

≥98%

form

methyl acetate solution (10 mg/mL)

shipped in

dry ice

storage temp.

−70°C

Quality Level

Biochem/physiol Actions

MAFP 是一种选择性、不可逆的钙依赖性和非钙依赖性胞浆型磷脂酶 a 2 抑制剂,但不是分泌型磷脂酶 a 2 。MAFP 也是一种强效乙酰胆碱酯酶抑制剂。

Preparation Note

为了更改溶剂,在温和的氮气流下蒸发乙酸甲酯,并立即加入选择的溶剂。

pictograms

FlameExclamation mark

signalword

Danger

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3

target_organs

Central nervous system

supp_hazards

存储类别

3 - Flammable liquids

wgk

WGK 2

flash_point_f

3.2 °F - closed cup

flash_point_c

-16 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

法规信息

危险化学品
此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

没有发现合适的版本?

如果您需要特殊版本,可通过批号或批次号查找具体证书。

已有该产品?

在文件库中查找您最近购买产品的文档。

访问文档库

Elizabeth R Cleverdon et al.
Bioorganic chemistry, 79, 98-106 (2018-05-09)
Ghrelin is a small peptide hormone that undergoes a unique posttranslational modification, serine octanoylation, to play its physiological roles in processes including hunger signaling and glucose metabolism. Ghrelin O-acyltransferase (GOAT) catalyzes this posttranslational modification, which is essential for ghrelin to
Yao-Fa Li et al.
In vitro cellular & developmental biology. Animal, 53(5), 421-429 (2017-04-30)
Prostaglandins (PGs) are oxygenated metabolites of arachidonic acid (AA) and two other C20 polyunsaturated fatty acids that serve as biochemical signals mediating physiological functions. We reported that PGs influence protein expression in insect cell lines, which prompted the question: do
Rose Cairns et al.
Experimental cell research, 358(2), 397-410 (2017-07-18)
Annexin A6 (AnxA6) has been implicated in the regulation of endo-/exocytic pathways, cholesterol transport, and the formation of multifactorial signaling complexes in many different cell types. More recently, AnxA6 has also been linked to triglyceride storage in adipocytes. Here we
Ryan M Wyatt et al.
The Journal of pharmacology and experimental therapeutics, 372(3), 339-353 (2019-12-11)
The serine hydrolase monoacylglycerol lipase (MAGL) is the rate-limiting enzyme responsible for the degradation of the endocannabinoid 2-arachidonoylglycerol (2-AG) into arachidonic acid and glycerol. Inhibition of 2-AG degradation leads to elevation of 2-AG, the most abundant endogenous agonist of the
Niina Aaltonen et al.
Biological procedures online, 22, 6-6 (2020-03-20)
Serine hydrolases (SHs) are a functionally diverse family of enzymes playing pivotal roles in health and disease and have emerged as important therapeutic targets in many clinical conditions. Activity-based protein profiling (ABPP) using fluorophosphonate (FP) probes has been a powerful

我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系客户支持