M3281
α-甲基-DL-酪氨酸甲酯 盐酸盐
≥95% (HPLC)
别名:
α-MT甲酯 盐酸盐, 2-甲基-4-羟基-DL-苯丙氨酸甲酯 盐酸盐, AMPT盐酸甲酯
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关于此项目
线性分子式:
4-(HO)C6H4CH2C(CH3)(NH2)CO2CH3 · HCl
化学文摘社编号:
分子量:
245.70
UNSPSC Code:
12352108
NACRES:
NA.32
PubChem Substance ID:
EC Number:
230-900-0
Beilstein/REAXYS Number:
5163031
MDL number:
Quality Level
assay
≥95% (HPLC)
mp
192 °C (dec.) (lit.)
solubility
DMSO: ≥20 mg/mL, clear, colorless to faintly yellow
storage temp.
−20°C
SMILES string
Cl[H].COC(=O)C(C)(N)Cc1ccc(O)cc1
InChI
1S/C11H15NO3.ClH/c1-11(12,10(14)15-2)7-8-3-5-9(13)6-4-8;/h3-6,13H,7,12H2,1-2H3;1H
InChI key
OOVDEPZODSXAMU-UHFFFAOYSA-N
Gene Information
human ... TH(7054)
相关类别
Application
α-甲基-DL-酪氨酸甲酯盐酸盐已被用于评估去甲肾上腺素的转换。
Biochem/physiol Actions
α-甲基-DL-酪氨酸（α-MT）可防止过度活性、嗅舔啃综合征、厌食症并改善苯丙胺的某些作用。它可抑制多巴胺的产生并防止突变体α-突触核蛋白刺激的细胞凋亡。
酪氨酸羟化酶抑制剂。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Central sympathetic innervations to visceral and subcutaneous white adipose tissue
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Antiamphetamine effects following inhibition of tyrosine hydroxylase
Weissman A
Journal of Pharmacology and Experimental Therapeutics, 151(3), 339-352 (1966)
W I Sivitz et al.
The American journal of physiology, 277(4 Pt 1), E668-E677 (1999-10-12)
To further investigate neural effects on leptin and uncoupling proteins (UCPs), we studied in vivo perturbations intended to block adrenergic input to peripheral tissues. We examined plasma leptin, leptin mRNA, and adipose and muscle UCP subtype mRNA in rats treated
T Bazzett et al.
Brain research, 580(1-2), 164-170 (1992-05-15)
Dopamine (DA) in the medial preoptic area (MPOA) has been shown to facilitate male rat sexual behavior. However, injections of the catecholamine (CA) neurotoxin 6-OHDA into the MPOA did not impair copulation in tests 3 days after injection. In the
C Nyquist-Battie et al.
The American journal of physiology, 271(4 Pt 2), H1547-H1554 (1996-10-01)
To assess the effects of long-term pressure overload on sympathetic presynaptic components in the left ventricle, young adult male rats were subjected to surgical constriction of the suprarenal abdominal aorta. At 4 and 8 wk postsurgery, but not at 1
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| M3281-1G | 04061834050087 |
| M3281-5G | 04061833428535 |
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