M3281
α-甲基-DL-酪氨酸甲酯 盐酸盐
≥95% (HPLC)
别名:
α-MT甲酯 盐酸盐, 2-甲基-4-羟基-DL-苯丙氨酸甲酯 盐酸盐, AMPT盐酸甲酯
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线性分子式:
4-(HO)C6H4CH2C(CH3)(NH2)CO2CH3 · HCl
化学文摘社编号:
分子量:
245.70
Beilstein:
5163031
EC 号:
MDL编号:
UNSPSC代码:
12352108
PubChem化学物质编号:
NACRES:
NA.32
质量水平
方案
≥95% (HPLC)
mp
192 °C (dec.) (lit.)
溶解性
DMSO: ≥20 mg/mL, clear, colorless to faintly yellow
储存温度
−20°C
SMILES字符串
Cl[H].COC(=O)C(C)(N)Cc1ccc(O)cc1
InChI
1S/C11H15NO3.ClH/c1-11(12,10(14)15-2)7-8-3-5-9(13)6-4-8;/h3-6,13H,7,12H2,1-2H3;1H
InChI key
OOVDEPZODSXAMU-UHFFFAOYSA-N
基因信息
human ... TH(7054)
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应用
α-甲基-DL-酪氨酸甲酯盐酸盐已被用于评估去甲肾上腺素的转换。
生化/生理作用
α-甲基-DL-酪氨酸(α-MT)可防止过度活性、嗅舔啃综合征、厌食症并改善苯丙胺的某些作用。它可抑制多巴胺的产生并防止突变体α-突触核蛋白刺激的细胞凋亡。
酪氨酸羟化酶抑制剂。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
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American Journal of Physiology. Regulatory, Integrative and Comparative Physiology, 306(6), R375-R386 (2014)
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The American journal of physiology, 271(4 Pt 2), H1547-H1554 (1996-10-01)
To assess the effects of long-term pressure overload on sympathetic presynaptic components in the left ventricle, young adult male rats were subjected to surgical constriction of the suprarenal abdominal aorta. At 4 and 8 wk postsurgery, but not at 1
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Dopamine (DA) in the medial preoptic area (MPOA) has been shown to facilitate male rat sexual behavior. However, injections of the catecholamine (CA) neurotoxin 6-OHDA into the MPOA did not impair copulation in tests 3 days after injection. In the
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