主要文件

查看所有文档

M3320

Monoclonal Anti-MBNL1 antibody produced in mouse

Name: Monoclonal Anti-MBNL1 antibody produced in mouse
Brand: SIGMA

~1 mg/mL, clone HL 1822 (3A4-1E9), purified immunoglobulin, buffered aqueous solution

别名:

Anti-CUG Triplet Repeat Expansion Double-stranded RNA-binding protein, Anti-EXP, Anti-KIAA0428, Anti-Muscleblind-like protein, Anti-Triplet-expansion RNA-binding protein

登录并加购，请在购物车里查看协议价、货期和发货地。

选择规格

变更视图

关于此项目

UNSPSC Code:

12352203

NACRES:

NA.41

MDL number:

MFCD09039233

Conjugate:

unconjugated

Clone:

HL 1822 (3A4-1E9), monoclonal

Application:

ARR, ICC, IHC, WB

Citations:

技术服务

需要帮助？我们经验丰富的科学家团队随时乐意为您服务。

让我们为您提供帮助

属性

biological source

mouse

Quality Segment

200

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

HL 1822 (3A4-1E9), monoclonal

form

buffered aqueous solution

mol wt

antigen ~42 kDa

species reactivity

monkey, mouse, human

concentration

~1 mg/mL

technique(s)

immunocytochemistry: suitable, immunohistochemistry: suitable, microarray: suitable, western blot: 0.2-0.5 μg/mL using HeLa nuclear cell extract

isotype

IgG1

UniProt accession no.

Q9NR56

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... MBNL1(4154)
mouse ... Mbnl1(56758)

说明

General description

Muscle blind-like 1 (MBNL1) is a homolog of human muscle blind like proteins. Proteins of the MBNL (muscleblind-like) family are mainly expressed in skeletal muscle neuronal tissues, thymus, liver and kidney.

Immunogen

recombinant muscleblind-like1 (MBNL1) fusion protein.

Application

Monoclonal Anti-MBNL1 antibody produced in mouse has been used in: immunoblotting, immunohistochemistry and immunocytochemistry

Biochem/physiol Actions

Proteins of the MBNL (muscleblind-like) family enhance inclusion or exclusion of specific exons on different pre-mRNAs by inhibiting the activity of CUG-BP and ETR-3-like factors (CELF proteins) bound to distinct intronic sites. MBNL1 may be implicated in the stimulation of muscle differentiation. Mice knockouts for the MBNL1 gene develop muscle, eye, and RNA splicing abnormalities that are characteristic of the neuromuscular disease myotonic dystrophy (DM) disease.

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Still not finding the right product?

Explore all of our products under Monoclonal Anti-MBNL1 antibody produced in mouse

— 或者 —

试用我们的产品选型工具工具缩小选择范围

存储类别

10 - Combustible liquids

怎么回事？

WGK 3

闪点 (F)

Not applicable

闪点 (°C)