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Merck
CN

M4004

N2-Methylguanosine

~95%

别名:

m2G

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经验公式(希尔记法):
C11H15N5O5
化学文摘社编号:
分子量:
297.27
UNSPSC Code:
41106305
PubChem Substance ID:
MDL number:
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InChI

1S/C11H15N5O5/c1-12-11-14-8-5(9(20)15-11)13-3-16(8)10-7(19)6(18)4(2-17)21-10/h3-4,6-7,10,17-19H,2H2,1H3,(H2,12,14,15,20)

SMILES string

CNC1=NC(=O)c2ncn(C3OC(CO)C(O)C3O)c2N1

InChI key

SLEHROROQDYRAW-UHFFFAOYSA-N

assay

~95%

form

solid

storage temp.

−20°C

Application

N2-Methylguanosine (m2is used to characterize and study the metabolism of naturally occurring methylated guanosine in RNAs.

存储类别

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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H A Heus et al.
European journal of biochemistry, 188(2), 275-281 (1990-03-10)
The 3'-terminal colicin fragments of 16S ribosomal RNA were isolated from Bacillus stearothermophilus and from its kasugamycin-resistant (ksgA) derivative lacking N6-dimethylation of the two adjacent adenosines in a hairpin loop. The fragment from the ksgA strain still contains a naturally
Belinda Westman et al.
RNA (New York, N.Y.), 11(10), 1505-1513 (2005-09-01)
The eukaryotic initiation factor eIF4E binds the mRNA 5' cap structure and has a central role during translational initiation. eIF4E and the mechanisms to control its activity have oncogenic properties and thus have become targets for anticancer drug development. A
Susumu Okamoto et al.
Molecular microbiology, 63(4), 1096-1106 (2007-01-24)
Streptomycin has been an important drug for the treatment of tuberculosis since its discovery in 1944. But numerous strains of Mycobacterium tuberculosis, the bacterial pathogen that causes tuberculosis, are now streptomycin resistant. Although such resistance is often mediated by mutations
Sarah F Mitchell et al.
Molecular cell, 39(6), 950-962 (2010-09-25)
Translational control is frequently exerted at the stage of mRNA recruitment to the initiating ribosome. We have reconstituted mRNA recruitment to the 43S preinitiation complex (PIC) using purified S. cerevisiae components. We show that eIF3 and the eIF4 factors not
Hua-Yu Li et al.
Journal of mass spectrometry : JMS, 44(5), 641-651 (2009-01-15)
Urinary-modified nucleosides have a potential role as cancer biomarkers for a number of malignant diseases. High performance liquid chromatography (HPLC) was combined with full-scan mass spectrometry, MS/MS analysis and accurate mass measurements in order to identify purine nucleosides purified from

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