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Merck
CN

M4255

3-Methoxy-L-tyrosine monohydrate

≥98% (HPLC)

别名:

4-Hydroxy-3-methoxy-L-phenylalanine, L-3-O-Methyl-DOPA

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关于此项目

经验公式(希尔记法):
C10H13NO4 H2O
化学文摘社编号:
分子量:
229.23
UNSPSC Code:
12352209
PubChem Substance ID:
NACRES:
NA.26
MDL number:
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产品名称

3-Methoxy-L-tyrosine monohydrate, powder

assay

≥98% (HPLC)

Quality Level

form

powder

application(s)

detection

storage temp.

2-8°C

SMILES string

COc1cc(C[C@H](N)C(O)=O)ccc1O

InChI

1S/C10H13NO4/c1-15-9-5-6(2-3-8(9)12)4-7(11)10(13)14/h2-3,5,7,12H,4,11H2,1H3,(H,13,14)/t7-/m0/s1

InChI key

PFDUUKDQEHURQC-ZETCQYMHSA-N

Biochem/physiol Actions

3-Methoxy-L-tyrosine is a metabolite of L-Dopa.
The major metabolite of L-DOPA via catechol O-methyltransferase (COMT). 3-methoxy-L-tyrosine is neither a substrate for nor an inhibitor of L-amino acid decarboxylase activity. Inhibition of COMT enhances the anti-Parkinson activity of L-DOPA.


存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Chiara Muzzi et al.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 62(4), 253-258 (2007-12-26)
Levodopa is the medication of choice for Parkinson's disease. The biological complexity of levodopa and of its main derivatives makes their determination important in the clinical field. The aim of this study was to develop an HPLC method for the



全球贸易项目编号

货号GTIN
M4255-250MG04061832424088
M4255-50MG04061834057598