M4758
（±）-6-甲基-5，6，7，8-四氢蝶呤 二盐酸盐
~95% (TLC)
别名:
6-MPH4, DL-2-氨基-4-羟基-6-甲基-5，6，7，8-四氢蝶啶 二盐酸盐
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关于此项目
经验公式（希尔记法）:
C7H11N5O · 2HCl
化学文摘社编号:
分子量:
254.12
UNSPSC Code:
12352204
NACRES:
NA.51
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
5648114
Assay:
~95% (TLC)
assay
~95% (TLC)
Quality Level
storage temp.
−20°C
SMILES string
Cl.Cl.CC1CNc2nc(N)nc(O)c2N1
InChI
1S/C7H11N5O.2ClH/c1-3-2-9-5-4(10-3)6(13)12-7(8)11-5;;/h3,10H,2H2,1H3,(H4,8,9,11,12,13);2*1H
InChI key
MKQLORLCFAZASZ-UHFFFAOYSA-N
Application
6-MPH4用于研究纹状体组织中一氧化氮（NO）合酶和自由基诱导的L-DOPA释放的机制。
Biochem/physiol Actions
酪氨酸水解酶的合成辅因子；也是苯丙氨酸和色氨酸羟化酶的辅因子；活性低于天然辅因子BH4
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
M Bauer et al.
Journal of neurochemistry, 82(5), 1300-1310 (2002-10-03)
Glial cell line-derived neurotrophic factor (GDNF) protects dopaminergic neurones against toxic and physical damage. In addition, GDNF promotes differentiation and structural integrity of dopaminergic neurones. Here we show that GDNF can support the function of primary dopaminergic neurones by triggering
Elizabeth A Gaskell et al.
PloS one, 4(3), e4801-e4801 (2009-03-12)
The genome of the protozoan parasite Toxoplasma gondii was found to contain two genes encoding tyrosine hydroxylase; that produces L-DOPA. The encoded enzymes metabolize phenylalanine as well as tyrosine with substrate preference for tyrosine. Thus the enzymes catabolize phenylalanine to
M Naoi et al.
Journal of chromatography, 427(2), 229-238 (1988-06-03)
A simple assay procedure for tyrosine hydroxylase activity in crude tissue samples was devised that requires minimal sample preparation and use of high-performance liquid chromatography with coulometric electrochemical detection. After incubation of enzyme samples, such as human brain homogenates or
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| M4758-100MG | 04061833272862 |
| M4758-50MG | 04061833272879 |