2′-C-甲基胞嘧啶核苷

Name: 2′-C-甲基胞嘧啶核苷
Brand: SIGMA

≥95% (HPLC), powder

别名:

2′-C-Methyl Cytidine, NM107

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所有图片(1)

About This Item

经验公式（希尔记法）:

C₁₀H₁₅N₃O₅

CAS Number:

20724-73-6

分子量:

257.24

MDL编号:

MFCD02682947

UNSPSC代码:

12352200

PubChem化学物质编号:

329817997

NACRES:

NA.77

质量水平

100

方案

≥95% (HPLC)

表单

powder

储存条件

desiccated

颜色

white to off-white

溶解性

H₂O: >20 mg/mL

储存温度

−20°C

SMILES字符串

C[C@@]1(O)[C@H](O)[C@@H](CO)O[C@H]1N2C=CC(N)=NC2=O

InChI

1S/C10H15N3O5/c1-10(17)7(15)5(4-14)18-8(10)13-3-2-6(11)12-9(13)16/h2-3,5,7-8,14-15,17H,4H2,1H3,(H2,11,12,16)/t5-,7-,8-,10-/m1/s1

InChI key

PPUDLEUZKVJXSZ-VPCXQMTMSA-N

生化/生理作用

2′-C-Methylcytidine is a potent inhibitor of the HCV NS5B RNA polymerase. 2′-C-Methylcytidine was the first nucleoside NS5B inhibitor that showed clinical efficacy. 2′-C-Methylcytidine was found to be effective against the 17D vaccine strain of yellow fever virus YFV in cell culture.

2′-C-Methylcytidine is a potent inhibitor of the HCV NS5B RNA polymerase.