M5391
美托洛尔 (+)-酒石酸盐
≥98% (titration), β1-adrenoceptor antagonist, powder
别名:
(±)1-(异丙氨基)-3-[p-(β-甲氧基乙基)苯氧基] -2-丙醇 (+)-酒石酸盐, Lopressor
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关于此项目
线性分子式:
(C15H25NO3)2 · C4H6O6
化学文摘社编号:
分子量:
684.81
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
260-148-9
MDL number:
Assay:
≥98% (titration)
Form:
powder
产品名称
美托洛尔 (+)-酒石酸盐, ≥98% (titration), powder
Quality Segment
assay
≥98% (titration)
form
powder
color
white to off-white
solubility
H2O: 50 mg/mL
originator
Novartis
SMILES string
O[C@H]([C@@H](O)C(O)=O)C(O)=O.COCCc1ccc(OCC(O)CNC(C)C)cc1.COCCc2ccc(OCC(O)CNC(C)C)cc2
InChI
1S/2C15H25NO3.C4H6O6/c2*1-12(2)16-10-14(17)11-19-15-6-4-13(5-7-15)8-9-18-3;5-1(3(7)8)2(6)4(9)10/h2*4-7,12,14,16-17H,8-11H2,1-3H3;1-2,5-6H,(H,7,8)(H,9,10)/t;;1-,2-/m..1/s1
InChI key
YGULWPYYGQCFMP-CEAXSRTFSA-N
Gene Information
human ... ADRB1(153)
General description
Metoprolol has antihypertensive and anti-ischemic properties. It is used to treat arrhythmias.
Application
(±)-Metoprolol (+)-tartrate salt has been used:
- to modulate the immunological parameters in various studies
- to study its effects onCa2+-calmodulin-dependent protein kinase II (CaMKII) activity in human and experimental heart failure (HF)
- to examine the contribution of the adrenergic receptors to the production of norepinephrine (NE)-mediated O2-
Biochem/physiol Actions
β1-adrenoceptor antagonist.
Features and Benefits
This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound was developed by Novartis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
Other Notes
Shelf-life of the powder is at least 4 years.
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signalword
Warning
hcodes
Hazard Classifications
Aquatic Chronic 2 - Repr. 2
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)