M5449
MKT-077
≥98% (HPLC), powder
别名:
1-乙基-2- [[3-乙基-5-（3-甲基-2 (3H)-苯并噻唑亚甲基）-4-氧代-2-噻唑亚基] 甲基]-氯化吡啶, FJ-776
登录查看公司和协议定价
关于此项目
线性分子式:
C21H22N3OS2Cl
CAS Number:
分子量:
432.00
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.77
质量水平
方案
≥98% (HPLC)
表单
powder
颜色
orange to red
溶解性
H2O: 10 mg/mL, clear
储存温度
2-8°C
SMILES字符串
CN(C1=C(S/2)C=CC=C1)C2=C3C(N(CC)/C(S\3)=C/C4=[N+](CC)C=CC=C4)=O.[Cl-]
InChI
1S/C21H22N3OS2.ClH/c1-4-23-13-9-8-10-15(23)14-18-24(5-2)20(25)19(27-18)21-22(3)16-11-6-7-12-17(16)26-21;/h6-14H,4-5H2,1-3H3;1H/q+1;/p-1/b21-19+;
InChI key
VSKYOTRJSLYFHX-UXJRWBAGSA-M
相关类别
生化/生理作用
MKT-077 是线粒体 hsp70 家族成员致死蛋白 (mot-2) n 的抑制剂
MKT-077 是线粒体 hsp70 家族成员致死蛋白 (mot-2) n 的抑制剂；它导致癌细胞选择性死亡。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Tuoen Liu et al.
PloS one, 12(2), e0170470-e0170470 (2017-02-09)
Myelodysplastic syndromes (MDS) are the most common adult myeloid blood cancers in the US. Patients have increased apoptosis in their bone marrow cells leading to low peripheral blood counts. The full complement of gene mutations that contribute to increased apoptosis
Victoria J Gennaro et al.
BMC cancer, 19(1), 258-258 (2019-03-25)
The oncoprotein MYC has the dual capacity to drive cell cycle progression or induce apoptosis, depending on the cellular context. BAG1 was previously identified as a transcriptional target of MYC that functions as a critical determinant of this cell fate
Jemma Day et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 33(12), 14611-14624 (2019-11-07)
Plasmodium falciparum is the most lethal of human-infective malaria parasites. A hallmark of P. falciparum malaria is extensive remodeling of host erythrocytes by the parasite, which facilitates the development of virulence properties such as host cell adhesion to the endothelial
Ahmed Edan Dhamad et al.
American journal of physiology. Cell physiology, 318(2), C289-C303 (2019-12-05)
Glucose-regulated protein 75 (GRP75) was first characterized in mammals as a heat shock protein-70 (HSP70) family stress chaperone based on its sequence homology. Extensive studies in mammals showed that GRP75 is induced by various stressors such as glucose deprivation, oxidative
Sunil Joseph et al.
Biology open, 6(4), 481-488 (2017-03-16)
Earlier studies suggested that
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持