Merck
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文件

M5820

Sigma-Aldrich

M344

≥98% (HPLC), powder

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别名:
4-(Dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]-benzamide, MS 344, D237, N-Hydroxy-7-(4-dimethylaminobenzoyl)-aminoheptanamide
经验公式（希尔记法）:
C16H25N3O3
CAS号:
251456-60-7
分子量:
307.39
MDL编号:
MFCD03453554
PubChem化学物质编号:
329818022
NACRES:
NA.77

质量水平

100

检测方案

≥98% (HPLC)

形式

powder

储存条件

protect from light

颜色

white to beige

溶解性

DMSO: 10 mg/mL, clear

储存温度

2-8°C

SMILES字符串

CN(C)c1ccc(cc1)C(=O)NCCCCCCC(=O)NO

InChI

1S/C16H25N3O3/c1-19(2)14-10-8-13(9-11-14)16(21)17-12-6-4-3-5-7-15(20)18-22/h8-11,22H,3-7,12H2,1-2H3,(H,17,21)(H,18,20)

InChI key

MXWDSZWTBOCWBK-UHFFFAOYSA-N

生化/生理作用

M344 is a HDAC inhibitor; subtype selective for HDAC6 over HDAC1. M344 inhibits HDAC (IC50 = 100 nM) and also inhibits hyperacetylation of histone H4, terminal cell differentiation, transcription (γ-globin), and tumor cell death.

特点和优势

This compound is a featured product for Gene Regulation research. Click here to discover more featured Gene Regulation products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

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说明
价格

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

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