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About This Item

MDL编号:
UNSPSC代码:
12352202
NACRES:
NA.77
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Product Name

巨噬细胞集落刺激因子 人, M-CSF, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture

生物来源

human

质量水平

重组

expressed in E. coli

方案

≥98% (SDS-PAGE and HPLC)

表单

lyophilized powder

效能

0.500-5.000 ng/mL ED50

质量

endotoxin tested

分子量

dimer 37 kDa

包装

pkg of 10 μg

技术

cell culture | mammalian: suitable

杂质

≤1.000 EU/μg

颜色

white

UniProt登记号

储存温度

−20°C

基因信息

human ... CSF1(1435)

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一般描述

Macrophage Colony-Stimulating Factor (M-CSF) is a hematopoietic growth factor, which modulates the proliferation, differentiation and functional activation of monocytes. It is produced by fibroblasts, endothelial cells and bone marrow stromal cells. MCSF stimulates the functions of mature monocytes and macrophages.

应用

Macrophage Colony-Stimulating Factor human has been used for the differentiation of bone marrow-derived macrophages (BMDMs) and human monocyte-derived macrophages (MDMs). It has also been used for cell culture.

生化/生理作用

Macrophage colony-stimulating factor (M-CSF) augments many of the physiological functions of macrophages, and support osteoclast differentiation.

其他说明

159 amino acids including N-terminal methionine (each monomer).

外形

Lyophilized from a sterile filtered buffered solution.

分析说明

The proliferative activity is tested in culture using the cytokine-dependent murine monocytic cell line M-NFS-60 cells.

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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