M6518
巨噬细胞集落刺激因子 人
≥98% (SDS-PAGE and HPLC), recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture
别名:
MCSF
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关于此项目
Biological source:
human
Recombinant:
expressed in E. coli
Assay:
≥98% (SDS-PAGE)
Form:
lyophilized powder
Mol wt:
dimer 37 kDa
Impurities:
≤1.000 EU/μg
产品名称
巨噬细胞集落刺激因子 人, M-CSF, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture
biological source
human
Quality Segment
recombinant
expressed in E. coli
assay
≥98% (SDS-PAGE)
form
lyophilized powder
quality
endotoxin tested
mol wt
dimer 37 kDa
packaging
pkg of 10 μg
technique(s)
cell culture | mammalian: suitable
impurities
≤1.000 EU/μg
color
white
suitability
suitable for (≤5.000 ng/ml (ED50))
UniProt accession no.
storage temp.
−20°C
General description
Macrophage Colony-Stimulating Factor (M-CSF) is a hematopoietic growth factor, which modulates the proliferation, differentiation and functional activation of monocytes. It is produced by fibroblasts, endothelial cells and bone marrow stromal cells. MCSF stimulates the functions of mature monocytes and macrophages.
Application
Macrophage Colony-Stimulating Factor human has been used for the differentiation of bone marrow-derived macrophages (BMDMs) and human monocyte-derived macrophages (MDMs). It has also been used for cell culture.
Biochem/physiol Actions
Macrophage colony-stimulating factor (M-CSF) augments many of the physiological functions of macrophages, and support osteoclast differentiation.
Physical form
Lyophilized from a sterile filtered buffered solution.
Analysis Note
The proliferative activity is tested in culture using the cytokine-dependent murine monocytic cell line M-NFS-60 cells.
Other Notes
159 amino acids including N-terminal methionine (each monomer).
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存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)